Endometriosis in premenarcheal girls who do not have an associated obstructive anomaly

Erica E. Marsh, Marsh EE, Laufer MR, Marc R. Laufer
Fertility and sterility · 2005 · vol. 83(3) , pp. 758–760 · doi:10.1016/j.fertnstert.2004.08.025 · PMID:15749511 · W1973939452
article OA: closed CC0 ⤵ 126 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This paper examined endometriosis in girls who had not yet menstruated and lacked obstructive anomalies.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

ObjectiveTo identify endometriosis as a cause of chronic pelvic pain in premenarcheal girls without an obstructive anomaly of the reproductive tract.DesignA case series.SettingTertiary-care academic pediatric hospital.Patient(s)Five premenarcheal girls with chronic (>6 months) pelvic pain and negative gastrointestinal workup.Intervention(s)Laparoscopic biopsies and resection, laser and/or cautery of all visible lesions.Main outcome measure(s)Visual presence of endometriosis and decrease in pelvic pain after destruction of lesions.Result(s)All subjects had laparoscopy with the identification of clear, red, and/or white lesions consistent with endometriosis based on the standard American Society for Reproductive Medicine Classification of Endometriosis. Postoperatively, all of the girls had marked improvement of their pelvic pain based on self-reported pain scales. Two of the subjects had subsequent repeat laparoscopies 6 and 8 years after their initial surgery, which revealed pathology-proven endometriosis.Conclusion(s)Endometriosis should be part of the differential diagnosis of chronic pelvic/lower abdominal pain in premenarcheal girls. The presence of lesions visibly consistent with endometriosis in premenarcheal girls without an obstructive anomaly supports the concept that some cases of endometriosis may result from an etiology other than retrograde menses.

My notes (saved in your browser only)

Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Endometrium Menarche Pelvic Pain Adolescent Biopsy Child Chronic Disease Endometriosis Endometrium Female Humans Pelvic Pain

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (18)

Cited by (50)

Source provenance

europepmc
last seen: 2026-09-05T06:14:40.014199+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:15:41.664291+00:00
License: CC0 · commercial use OK