Adolescent endometriosis
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This paper discusses adolescent endometriosis, examining its prevalence, diagnostic challenges, and therapeutic approaches in young individuals.
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Abstract
Endometriosis is a common finding in adolescents who have a history of chronic pelvic pain or dysmenorrhoea resistant to medical treatment, however the exact prevalence is unknown. Both early/superficial and advanced forms of endometriosis are found in adolescents, including ovarian endometriomas and deep endometriotic lesions. Whilst spontaneous resolution is possible, recent reports suggest that adolescent endometriosis can be a progressive condition, at least in a significant proportion of cases. It is also claimed that deep endometriosis has its roots in adolescence. Optimum treatment is far from clear and long term recurrence is still a significant problem. The most frequently reported treatment approach in the published literature is a combination of surgery and postoperative hormonal treatment with the combined oral contraceptives, progestins, levonorgestrel intrauterine system or gonadotrophin releasing hormone analogues. Use of gonadotrophin releasing hormone analogues and long term progestins should be carefully considered due to concerns over continuing bone formation in this age group. There is currently no consensus as to whether surgery should be avoided as much as possible to prevent multiple operations in the long term, or surgical treatment should be considered at an early stage before more severe lesions develop. Further research is required to determine which approach would offer a better long term outcome.
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Cited by (40)
- Missing Out: A Qualitative Study Exploring Adolescents’ and Young Women’s Experiences of Endometriosis 2026
- Adolescent Endometriosis and Chronic Pelvic Pain 2026
- Endometriosis in Adolescents 2025
- Hormonal Treatment of Endometriosis: A Narrative Review 2025
- Current Insights into Endometriosis: Hormonal Management, Clinical Outcomes, and Opportunities for Progress 2025
- Diaphragmatic endometriosis associated with pelvic endometriosis: a case report 2025
- Ultrasound image of ovarian endometrioma as an indicator of external genital endometriosis 2024
- Exploring the interface between adolescent dysmenorrhoea and endometriosis: a protocol for a cohort and nested case-control study within the QResearch Database 2023
- Medikamentöse Therapie der Endometriose – ein Update 2023
- Proposal for targeted, neo-evolutionary-oriented secondary prevention of early-onset endometriosis and adenomyosis. Part II: medical interventions 2023
- Pain Levels of Women Diagnosed with Endometriosis: Is There a Difference in Younger Women? 2022
- Educational Intervention and Referral for Early Detection of Endometriosis among Technical Secondary Schools Students 2022
- Medical and Behavioral Aspects of Adolescent Endometriosis: A Review of the Literature 2022
- Medikamentöse Therapie der Endometriose – ein Update 2022
- Feasibility of two robotic single‐site surgery techniques for adolescent endometriosis: Focal versus butterfly 2021
- Pharmacological Management of Endometriosis-related Pain: The Expert Opinion 2021
- Clinical Aspects of Adolescent Endometriosis 2021
- Management of Endometriosis in Teenagers 2020
- Adolescent Endometriosis: Fertility Outcomes 2020
- Clinical Evaluation and Preoperative Considerations in Adolescent Girls with Endometriosis 2020
- Molecular Mechanisms Underlying Adolescent Endometriosis and Advancements in Medical Management 2020
- Comorbidities in Adolescent Women with Endometriosis 2020
- Fertility Preservation in Adolescents with Endometriosis 2020
- Treatment algorithm for women with endometriosis in a certified Endometriosis Unit 2020
- Endometriosis in adolescence: Early manifestation of the traditional disease or a unique variant? 2020
- Dysmenorrhea and Endometriosis: Diagnosis and Management in Adolescents 2020
- Lack of Data-driven Treatment Guidelines and Wide Variation in Management of Chronic Pelvic Pain in Adolescents and Young Adults 2020
- Laparoscopic Surgery in Adolescent Endometriosis 2020
- Standards Used by a Clinical and Scientific Endometriosis Center for the Diagnosis and Therapy of Patients with Endometriosis 2019
- Cancer-associated mutations in endometriosis: shedding light on the pathogenesis and pathophysiology 2019
- When more is not better: 10 ‘don’ts’ in endometriosis management. An ETIC* position statement 2019
- Relationship between Patient Age and Disease Features in a Prospective Cohort of 1560 Women Affected by Endometriosis 2019
- Expression of the TFDP1 gene in the endometrium of women with deep infiltrating endometriosis 2019
- Ovarian endometriosis and infertility: in vitro fertilization (IVF) or surgery as the first approach? 2018
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- europepmc
- last seen: 2026-09-10T06:15:44.054944+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:21:00.404924+00:00
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