Adolescent Endometriosis and Chronic Pelvic Pain
This review explores recent advances in understanding adolescent endometriosis and its role in chronic pelvic pain, covering symptom patterns, pain mechanisms, and multimodal treatment approaches.
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This paper is a narrative review examining adolescent endometriosis and its relationship to chronic pelvic pain, using high-level synthesis of evidence on symptom patterns, proposed mechanisms of pain, and treatment approaches. It reports growing support for earlier, largely noninvasive clinical diagnosis in adolescents rather than routinely delaying care for surgical confirmation, while noting that specialized imaging and biomarkers still lack the sensitivity to definitively rule out endometriosis and are not yet validated in this population. The review also highlights central sensitization and biopsychosocial factors as contributors to pain persistence, which may explain overlap between endometriosis symptoms and chronic pelvic pain. This paper is centrally about endometriosis in adolescents and chronic pelvic pain.
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