Trauma and endometriosis. A review. May we explain surgical phenotypes and natural history of the disease?

Michel Canis, M Canis, Nicolas Bourdel, N Bourdel, Bourdel N, C. Houlle, Houlle C, A.-S. Gremeau, A.-S. Grémeau, Gremeau AS, R. Botchorishvili, Matsuzaki S, Sachiko Matsuzaki, S Matsuzaki
Journal of gynecology obstetrics and human reproduction · 2017 · vol. 46(3) , pp. 219–227 · doi:10.1016/j.jogoh.2016.12.008 · PMID:28403918 · W2586499392
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This review examines the relationship between trauma and endometriosis, aiming to explain surgical phenotypes and the disease's natural history.

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Abstract

ObjectiveThe study was performed to evaluate whether trauma is an initial event of development of endometriosis.MethodUsing Medline database from January 1960 up to December 2014, a systematic review was made of all published studies using the keywords trauma, healing, injury, infection, hyperperistaltism, stretch and endometriosis, adenomyosis and trauma. Studies and review articles written in French and/or in English related to the topic were included and reviewed independently by two authors.ResultsThe role of trauma is well-established for endometriotic lesions diagnosed in surgical scars. Various traumas including delivery, uterine curettage or incision, intraperitoneal hemorrhage, or occult pelvic inflammatory diseases could be involved to explain other localizations of the disease. Many data suggested that the healing process, particularly growth factors and the associated estrogen production, may facilitate the implantation and the growth of ectopic endometrial cells. After the initial, a traumatic event, the phenotype of the disease would depend on the tissue in which the endometriotic lesion grows.ConclusionsThe present literature review may support a potential role of a trauma as an initial event of endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Animals Cesarean Section Cicatrix Cicatrix Curettage Curettage Delivery, Obstetric Delivery, Obstetric Endometriosis Female Genitalia, Female Genitalia, Female Hemorrhage Hemorrhage Humans Pelvic Inflammatory Disease Pelvic Inflammatory Disease Peritoneal Diseases Peritoneal Diseases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

Cited by (23)

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License: CC0 · commercial use OK