Characteristics of uterine contractility during menses in women with mild to moderate endometriosis

Carlo Bulletti, Bulletti C, De Ziegler D, Dominique de Ziegler, V. Polli, Polli V, Valeria Polli, Del Ferro E, Elena Del Ferro, Simone Palini, Palini S, Carlo Flamigni, Flamigni C, C Flamigni
Fertility and Sterility · 2002 · vol. 77(6) , pp. 1156–1161 · doi:10.1016/s0015-0282(02)03087-x · PMID:12057721 · W2133378494
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This study characterized uterine contractility during menses in women with mild to moderate endometriosis.

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Abstract

ObjectiveTo establish the role of uterine contractions in retrograde menstruation with subsequent abdominal implantation of endometrial tissue.DesignControlled prospective study.SettingUniversity hospital-based study.Patient(s)Infertile women with (n = 22) and without (n = 22) endometriosis.Main outcome measure(s)Frequency, amplitude, and basal pressure tone of uterine contractions; correlation of contractions with retrograde bleeding and presence of viable endometrial cells; and dysmenorrhea before and 3 and 24 months after surgery.Result(s)Compared with controls, patients with endometriosis had uterine contractions with higher frequency (22.73 +/- 5.66 osc/10 min vs. 11.09 +/- 3.26 osc/10 min), amplitude (20.83 +/- 3.94 mm Hg vs. 6.77 +/- 2.83 mm Hg), and basal pressure tone (50.14 +/- 16.30 mm Hg vs. 24.68 +/- 6.14 mm Hg). Dysmenorrhea was scored as 4.09 +/- 1.44 in patients with endometriosis and 0.86 +/- 1.42 in controls. Retrograde bleeding was found in 73% of patients with endometriosis vs. 9% of controls, and only 45% of patients with endometriosis had viable endometrial cells in the cul-de-sac.Conclusion(s)Endometriosis may result from abnormal myometrial contractility through tubal transportation, dissemination, and implantation of endometrial viable cells into the abdomen.

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Condition tags

dysmenorrheaendometriosis

MeSH descriptors

Endometriosis Menstruation Uterine Contraction Adult Dysmenorrhea Dysmenorrhea Dysmenorrhea Endometriosis Endometriosis Endometriosis Endometrium Endometrium Female Humans Incidence Menstruation Severity of Illness Index Uterine Contraction Uterine Hemorrhage Uterine Hemorrhage

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (50)

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