Obstetric complications after laparoscopic excision of posterior deep infiltrating endometriosis: a case–control study

Konstantinos Nirgianakis, Nirgianakis K, Maria Luisa Gasparri, Anda-Petronela Radan, Anda‐Petronela Radan, Anna-Sophie Villiger, Anna Villiger, Brett McKinnon, Beatrice Mosimann, Andrea Papadia, Michael D. Mueller, Mueller MD
Fertility and sterility · 2018 · vol. 110(3) , pp. 459–466 · doi:10.1016/j.fertnstert.2018.04.036 · PMID:30098698 · W2885646581
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This case-control study compared obstetric complications in women who underwent laparoscopic excision of posterior deep infiltrating endometriosis versus women without endometriosis.

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Abstract

ObjectiveTo study obstetric outcomes and complications in women with previously excised posterior deep infiltrating endometriosis (DIE) in comparison with women without endometriosis.DesignMatched case-control study.SettingTertiary-level academic center.Patient(s)All surgeries for endometriosis performed in the Department of Gynecology and Gynecological Oncology, University of Bern between March 2004 and July 2015, were assessed. Inclusion criteria included complete laparoscopic excision of posterior DIE. Exclusion criteria included concomitant hysterectomies, refusal to participate, and patients lost to follow-up. Each subsequent pregnancy was matched to three controls by maternal age, parity, history of cesarean, and mode of conception.Intervention(s)None.Main outcome measure(s)Obstetric complications.Result(s)Among 841 patients with surgically diagnosed endometriosis, 125 satisfied the inclusion and exclusion criteria. Of these, 73 pregnancies resulted, although a further 11 patients were excluded owing to early miscarriages or extrauterine pregnancies. The final study cohort included 62 singleton pregnancies matched to 186 controls. The analysis identified an increased risk of placenta previa, gestational hypertension, and intrauterine growth restriction for the case group. The possibility of successful vaginal delivery was similar between groups. Moreover, no significant increase in risk of maternal and neonatal delivery complications, except for a slightly higher postpartum blood loss in the case group, was observed.Conclusion(s)Despite previous surgical excision, women with history of DIE present a higher risk of placenta previa, gestational hypertonia, and intrauterine growth restriction during pregnancy. Previous surgery for DIE does not seem to predispose to failed vaginal delivery.

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Condition tags

endometriosisdie_deep_infiltrating

MeSH descriptors

Delivery, Obstetric Endometriosis Endometriosis Laparoscopy Obstetric Labor Complications Pregnancy Outcome Adult Case-Control Studies Delivery, Obstetric Delivery, Obstetric Endometriosis Endometriosis Female Humans Laparoscopy Laparoscopy Obstetric Labor Complications Obstetric Labor Complications Pregnancy Pregnancy Complications

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (38)

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