Adverse pregnancy and neo-natal outcomes after assisted reproductive treatment in patients with pelvic endometriosis: a case–control study

Marianne Jacques, Thomas Fréour, Thomas Freour, Freour T, P. Barrière, Paul Barriere, Barriere P, Stéphane Ploteau, Ploteau S
Reproductive biomedicine online · 2016 · vol. 32(6) , pp. 626–634 · doi:10.1016/j.rbmo.2016.03.005 · PMID:27068240 · W2323314925
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This case-control study investigated pregnancy and neonatal outcomes in patients with pelvic endometriosis undergoing assisted reproductive treatments, comparing them to a control group.

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Abstract

To assess the impact of endometriosis on obstetric outcomes and to determine whether the severity, location and surgical treatment of the disease before the pregnancy had an impact on the prevalence of these disorders, a monocentric, case-control study was performed. In total, 113 pregnancies obtained by assisted reproductive treatment among patients with endometriosis were matched with control selected among assisted reproductive treatment pregnancies due to male infertility. The main result measures were pregnancy outcome at the obstetrical and neo-natal levels. The incidence of first trimester bleeding, pre-eclampsia, premature delivery threat, pelvic pain and Caesarean section was significantly higher (P < 0.05) in women with endometriosis. Except for gestational diabetes and intrauterine growth restriction (IUGR), the severity, location of lesions and surgical treatment of endometriosis did not have an impact on either pregnancy outcome or risk of obstetric complications. The IUGR is mainly due to deep locations and the revised American Fertility Society (rAFS) stages III-IV. Newborns with a mother suffering from endometriosis are at greater risk of being premature, smaller for their gestational age and more frequently hospitalized than the control group. Deep location of endometriosis is associated with more prematurity, hospitalization and smaller birthweight than ovarian locations.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Infertility, Female Pelvic Pain Reproductive Techniques, Assisted Adult Case-Control Studies Cesarean Section Endometriosis Endometriosis Female Humans Incidence Infant, Premature Infertility, Female Infertility, Female Infertility, Male Infertility, Male Male Pelvic Pain Pelvic Pain

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (39)

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