Fertility, Pregnancy Rate, and Neonatal Outcome of Patient with Adenomyosis
Adenomyosis is associated with decreased pregnancy rates and increased miscarriage rates after ART, along with higher risks of preeclampsia, premature delivery, and other adverse neonatal outcomes.
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This paper systematically reviewed 17 observational studies (searching MEDLINE, PubMed, and Cochrane up to April 2022) evaluating how adenomyosis affects fertility, assisted reproductive technology (ART) outcomes, and neonatal and obstetric complications. Across ART, adenomyosis was associated with a reduced clinical pregnancy rate (OR 0.69, 95% CI 0.51–0.94) and an increased miscarriage rate (OR 2.17, 95% CI 1.25–3.79), with the lower pregnancy rate particularly evident in studies using shorter GnRH downregulation regimens; similar patterns were reported after age adjustment. Adenomyosis was also linked to higher risks of preeclampsia, premature delivery, cesarean section, fetal malpresentation, small-for-gestational-age infants, and postpartum hemorrhage after adjustments for age and mode of conception. The paper’s main caveat is that the evidence comes from observational studies. This paper is centrally about adenomyosis and its effects on fertility, pregnancy outcomes, and neonatal outcomes.
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References (25)
- Adenomyosis and adverse perinatal outcomes: increased risk of second trimester miscarriage, preeclampsia, and placental malposition via openalex
- Adenomyosis and risk of preterm delivery via openalex
- Adenomyosis has no adverse effects on IVF/ICSI outcomes in women with endometriosis treated with long-term pituitary down-regulation before IVF/ICSI via openalex
- Adverse pregnancy outcomes associated with adenomyosis with uterine enlargement via openalex
- Does presence of adenomyosis affect reproductive outcome in IVF cycles? A retrospective analysis of 973 patients via openalex
- Influence of adenomyosis on pregnancy and perinatal outcomes in women with endometriosis via openalex
- Long-term pituitary downregulation before frozen embryo transfer could improve pregnancy outcomes in women with adenomyosis via openalex
- MR imaging of diffuse adenomyosis changes after GnRH analog therapy via openalex
- Obstetric complications after laparoscopic excision of posterior deep infiltrating endometriosis: a case–control study via openalex
- Pregnancy rate in women with adenomyosis undergoing fresh or frozen embryo transfer cycles following gonadotropin-releasing hormone agonist treatment via openalex
- Relationship between the magnetic resonance imaging appearance of adenomyosis and endometriosis phenotypes via openalex
- Reproductive, obstetric, and perinatal outcomes of women with adenomyosis and endometriosis: a systematic review and meta-analysis via openalex
- Risk of preterm birth, low birthweight and small‐for‐gestational‐age infants in pregnancies with adenomyosis: A cohort study of the Japan Environment and Children's Study via openalex
- Role of transvaginal sonography and magnetic resonance imaging in the diagnosis of uterine adenomyosis via openalex
- Sonographic classification and reporting system for diagnosing adenomyosis via openalex
- Symptoms and classification of uterine adenomyosis, including the place of hysteroscopy in diagnosis via openalex
- The effect of adenomyosis on in vitro fertilisation and intra-cytoplasmic sperm injection treatment outcome via openalex
- To suppress or not to suppress? If that is the question, has it been answered? via openalex
- Ultrasound diagnosed adenomyosis has a negative impact on successful implantation following GnRH antagonist IVF treatment via openalex
- Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis via openalex
- Uterine junctional zone at magnetic resonance imaging: A predictor of <i>in vitro</i> fertilization implantation failure via openalex
- W2753073405 via openalex
- W2916530067 via openalex
- W2525448258 via openalex
- W2002029293 via openalex
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