Association between surgically diagnosed endometriosis and adverse pregnancy outcomes

Innie Chen, Lalani S, Shifana Lalani, Xie RH, Ri-Hua Xie, Ri‐hua Xie, Minxue Shen, Singh SS, Sukhbir S. Singh, Shi Wu Wen, Shi-Wu Wen, Wen SW
Fertility and sterility · 2017 · vol. 109(1) , pp. 142–147 · doi:10.1016/j.fertnstert.2017.09.028 · PMID:29198848 · W2769753217
article OA: bronze CC0 ⤵ 41 in-corpus citations
🔓 Open OA copy View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This study investigated the link between surgically diagnosed endometriosis and adverse pregnancy outcomes, finding a significant association with certain complications.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

ObjectiveTo examine the association between surgically diagnosed endometriosis and pregnancy outcomes in subsequent pregnancies.DesignRetrospective cohort study of women who delivered a singleton live birth from 2003 to 2013 in Ottawa, Ontario, Canada.SettingTertiary level academic center.Patient(s)Pregnant women with surgically diagnosed endometriosis were identified using International Classification of Diseases-10 codes from previous hospital admissions and were compared with pregnant women with no prior admission for endometriosis for the occurrences of adverse pregnancy outcomes.Intervention(s)Observational study.Main outcome measure(s)Gestational hypertension, preeclampsia, placenta previa, placental abruption, postpartum hemorrhage, preterm birth, low birth weight, small for gestational age, and neonatal intensive care unit admission.ResultsAmong the 52,202 eligible mother-infant pairs, we identified 469 mothers with surgically diagnosed endometriosis from a previous hospital encounter. Compared with women without endometriosis, women with endometriosis were on average older and were more likely to be primiparous, have lower gravidity, have a history spontaneous abortion, conceive with assisted reproductive technology, and reside in areas with higher neighborhood income and lower proportion of immigrants. Women with endometriosis were found to have an elevated risk of placenta previa (relative risk [RR], 3.30; 95% confidence interval [CI], 1.65-5.40) and cesarean delivery (RR, 1.24; 95% CI, 1.10-1.40). After adjustment for potential confounding factors, women with endometriosis were found to have a significantly elevated risk of placenta previa compared with women without endometriosis (adjusted RR, 2.54; 95% CI, 1.39-4.64).Conclusion(s)This study identifies baseline demographic differences between women with and without endometriosis and suggests that women affected by endometriosis have an independently elevated risk of placenta previa in pregnancy.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Endometriosis Placenta Previa Adult Age Factors Chi-Square Distribution Comorbidity Endometriosis Endometriosis Endometriosis Endometriosis Female Humans Logistic Models Multivariate Analysis Odds Ratio Ontario Parity Placenta Previa Placenta Previa Placenta Previa

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (28)

Cited by (42)

Source provenance

europepmc
last seen: 2026-08-25T06:10:03.373225+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:20:07.505861+00:00
License: CC0 · commercial use OK