Complications during pregnancy and delivery in women with untreated rectovaginal deep infiltrating endometriosis

Caterina Exacoustos, Exacoustos C, C. Exacoustós, I. Lauriola, Lauriola I, Ilaria Lauriola, Lucia Lazzeri, Giovanna De Felice, De Felice G, G. De Felice, Errico Zupi, Zupi E
Fertility and sterility · 2016 · vol. 106(5) , pp. 1129–1135.e1 · doi:10.1016/j.fertnstert.2016.06.024 · PMID:27445198 · W2501829607
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study investigated pregnancy and delivery complications in women with untreated rectovaginal deep infiltrating endometriosis and identified associated risks.

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Abstract

ObjectiveTo study outcomes and complications during pregnancy and at delivery in women with a posterior deep infiltrating endometriosis (DIE) nodule persisting after surgery and diagnosed at transvaginal sonography (TVS) in comparison with a control group of women without endometriosis.DesignMulticenter observational and cohort study.SettingUniversity hospital.Patient(s)Women (n = 200) with a posterior DIE nodule equal or more than 2 cm centimeters in size who desired a pregnancy and a control group of women (n = 300) with no previous recorded diagnosis of endometriosis who delivered in our clinic during the same time period.Intervention(s)Patient data collected from medical charts and by phone interviews.Main outcome measure(s)Evaluation of complications during pregnancy and delivery.Result(s)Of the 101 women with a posterior DIE nodule, 52 become pregnant among whom 25 used assisted reproductive technology. Of these 52 pregnancies, 11 ended in an early abortion, and 41 delivered a baby; 13 (31.7%) had a premature delivery, 7 (17.8%) a placenta praevia, and 28 (68.2%) had a cesarean delivery. When compared with the control group, the women with endometriosis had a higher risk of pregnancy complicated by preterm birth, placenta previa, placental abruption, and hypertension. Cesarean delivery and complications during surgery (hysterectomy, hemoperitoneum, and bladder injuries) were statistically significantly more frequent in women with endometriosis than in controls.Conclusion(s)Women with an incomplete removal of posterior DIE have a high complications rate during pregnancy and delivery.

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Condition tags

endometriosisdie_deep_infiltrating

MeSH descriptors

Delivery, Obstetric Endometriosis Infertility, Female Parturition Pregnancy Complications Rectal Diseases Vaginal Diseases Adult Case-Control Studies Cesarean Section Cesarean Section Delivery, Obstetric Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female Infertility, Female Infertility, Female

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Cited by (50)

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