Inflammation: a link between endometriosis and preterm birth

Felice Petraglia, Arcuri F, Felice Arcuri, de Ziegler D, Dominique de Ziegler, Charles Chapron, Chapron C
Fertility and sterility · 2012 · vol. 98(1) , pp. 36–40 · doi:10.1016/j.fertnstert.2012.04.051 · PMID:22658345 · W2054323092
review OA: closed CC0 ⤵ 71 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This review explores the potential link between endometriosis and preterm birth, focusing on the shared inflammatory mechanisms that may contribute to both conditions.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Endometriosis is a chronic inflammatory disease affecting women's health. Pain and infertility are the major symptoms caused by a hormonal/immunological dysfunction, which causes an endometrial impairment. The same pathogenetic mechanisms are also associated with preterm birth: hormones, cytokines, neurohormones, and growth factors interact in modulating extracellular matrix and prostaglandin secretion, thus activating the inflammatory process in placental membranes and myometrium. An overlap of molecules and mechanisms may explain the evidence that preterm birth is a common outcome in pregnant patients with endometriosis.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Endometriosis Inflammation Pregnancy Complications Premature Birth Uterine Diseases Endometriosis Endometriosis Female Humans Infant, Newborn Inflammation Inflammation Pregnancy Pregnancy Complications Pregnancy Complications Premature Birth Premature Birth Risk Factors Uterine Diseases Uterine Diseases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (58)

Cited by (50)

Source provenance

europepmc
last seen: 2026-07-27T06:15:28.040536+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:16:11.197438+00:00
License: CC0 · commercial use OK