‘There will be blood’† A proof of concept for the role of haemorrhagic corpora lutea in the pathogenesis of endometriosis

Paolo Vercellini, Camilla Erminia Maria Merli, Paola Viganò
Human reproduction open · 2024 · vol. 2024(3) , pp. hoae035 · doi:10.1093/hropen/hoae035 · PMID:38905004 · PMC11189658 · W4399117893
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study investigated the role of hemorrhagic corpus luteum in endometriosis pathogenesis, finding that women with intra-abdominal bleeding and hemorrhagic functional ovarian cysts were more likely to develop deep infiltrating endometriosis.

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Abstract

This cohort study follows the publication of a previous prospective pilot study by the same research group.Bean et al. (2019) followed 35 women with severe acute lower abdominal pain and detected de novo DIE at ultrasound follow-up in 4/6 (67%) of patients with evidence of haemoperitoneum compared with 1/29 (3%) of those without haemoperitoneum at baseline assessment.Seven of the eight women who presented with intra-abdominal bleeding had a haemorrhagic functional ovarian cyst.Two of these eight patients did not complete the follow-up.Pooling data from the above studies, 11/21 (52%; 95% CI, 32% to 72%) patients presenting

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Condition tags

endometriosisdie_deep_infiltrating

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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