Malignant degeneration of perineal endometriosis in episiotomy scar, case report and review of the literature

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This case report describes malignant degeneration of perineal endometriosis within an episiotomy scar and reviews the relevant literature on this rare occurrence.

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Abstract

Although malignant degeneration of cutaneous endometriosis is rare at only 0.3-1% in endometriosis surgical scars, diagnosis and management need to be defined. A case of malignant degeneration of perineal endometriosis is reported, with a review of literature. Physiopathology, epidemiological data, diagnostic and therapeutic methods are discussed for malignant degeneration of cutaneous endometriosis. Any scar lesion that evolves in response to the menstrual cycle should be considered endometriosis until proven otherwise, and thus could require surgical resection, with histological analysis. A history of cutaneous endometriosis with frequent recurrences can indicate malignant degeneration. All cases require long-term clinical follow-up because, despite the rarity of this diagnosis, the delay between benign endometriosis and malignant transformation can vary from a few months to over 40 years.

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Condition tags

endometriosis

MeSH descriptors

Cicatrix Cystadenocarcinoma, Papillary Endometriosis Episiotomy Perineum Perineum Cicatrix Cystadenocarcinoma, Papillary Cystadenocarcinoma, Papillary Cystadenocarcinoma, Papillary Endometriosis Episiotomy Female Humans Middle Aged

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (24)

Cited by (38)

Source provenance

europepmc
last seen: 2026-08-26T06:08:41.316361+00:00
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License: CC0 · commercial use OK