Clear Cell Adenocarcinoma Arising in Endometriosis of a Previous Episiotomy Site
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Abstract
In Brief BACKGROUND: Malignant transformation of endometriosis in an episiotomy site is rare. CASE: A 42-year-old woman presented with a palpable mass, 2.5 cm in size, just inside the posterior commissure of the vagina, at the site of a previous episiotomy for a vaginal delivery. Three years previously, an endometriotic cyst had been excised at the same site, and the patient had been treated with a gonadotropin-releasing hormone analogue for 6 months. Biopsy revealed a clear cell adenocarcinoma arising in endometriosis. The patient underwent radical surgery alone without adjuvant therapy. At 10-month follow-up, there was no evidence of recurrence. CONCLUSION: Patients who experience a recurrence of extragonadal endometriosis after prior therapy should be monitored carefully for malignant degeneration. A clear cell carcinoma arose in endometriosis of a previous episiotomy site.
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References (9)
- A case of clear cell carcinoma arising in extragonadal endometriosis via openalex
- Clear cell carcinoma arising in a Cesarean section scar endometriosis: a case report via openalex
- Clear Cell Carcinoma Arising in Extragonadal Endometriosis in a Caesarean Section Scar during Pregnancy via openalex
- Clear cell carcinoma arising in extraovarian endometriosis: Report of three cases and review of the literature via openalex
- Cystadenocarcinoma of the abdominal wall following caesarean section: case report and review of the literature via openalex
- Malignant degeneration of perineal endometriosis in episiotomy scar, case report and review of the literature via openalex
- Malignant neoplasms arising in endometriosis via openalex
- W6675344820 via openalex
- W1976783223 via openalex
Cited by (8)
- Diagnosis and Treatment of Vulvo-Perineal Endometriosis: A Systematic Review 2021
- Comparison of clear cell carcinoma and benign endometriosis in episiotomy scar - two cases report and literature review 2020
- Endometriosis-associated Extraovarian Malignancies: A Challenging Question for the Clinician and the Pathologist 2020
- Spontaneous Vulvar Endometriosis of Labium Minus: A Case Report and Review of Literature 2020
- Malignant Transformation of Vaginal Endometriosis - A Review of Literature 2016
- Clear cell carcinoma arising in previous episiotomy scar: a case report and review of the literature 2016
- Novel insights on the malignant transformation of endometriosis into ovarian carcinoma 2014
- Clear cell adenocarcinoma arising from endometriosis in abdominal wall cesarean section scar: a case report and review of the literature 2012
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- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- unpaywall
- last seen: 2026-06-02T02:00:03.124865+00:00
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