A case of clear cell carcinoma arising in extragonadal endometriosis
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This paper reports a rare case of clear cell carcinoma originating from extragonadal endometriosis.
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Abstract
Malignancy developing in extragonadal endometriosis is rare with the majority of cases being endometrioid adenocarcinomas. We present a 54-year-old woman who developed a clear cell carcinoma in her perineum, 25 years after excision of a perineal endometrioma in an episiotomy scar. Treatment involved radiotherapy and surgery, with a view to preserving vaginal function. Where benign extragonadal endometriosis occurs, the potential for malignant transformation persists even years after primary treatment.
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References (8)
- Clear Cell Carcinoma Arising in Extragonadal Endometriosis in a Caesarean Section Scar during Pregnancy via openalex
- Clear cell carcinoma arising in extraovarian endometriosis: Report of three cases and review of the literature via openalex
- Clear cell carcinoma of the inguinal region arising from endometriosis via openalex
- ENDOMETRIAL CARCINOMA OF THE OVARY, ARISING IN ENDOMETRIAL TISSUE IN THAT ORGAN via openalex
- Endometriosis and ovarian cancer via openalex
- Malignancy arising in extragonadal endometriosis.A case report and summary of the world literature via openalex
- Malignant extraovarian endometriosis: Two case reports and review of the literature via openalex
- W2029131024 via openalex
Cited by (18)
- Episiotomy site scar endometriosis: a case report and review of literature 2022
- Diagnosis and Treatment of Vulvo-Perineal Endometriosis: A Systematic Review 2021
- Comparison of clear cell carcinoma and benign endometriosis in episiotomy scar - two cases report and literature review 2020
- Perianal Endometriosis: Five Case Reports 2018
- Clear cell carcinoma arising in previous episiotomy scar: a case report and review of the literature 2016
- A Case of Endometriosis in Episiotomy Scar with Anal Sphincter Involvement and Extension into Ischiorectal Fossa 2014
- Perineal Endometrioma with anal sphincter involvement. A case report 2013
- Clear cell adenocarcinoma arising from endometriosis in abdominal wall cesarean section scar: a case report and review of the literature 2012
- Endometrioma perianal involucrando esfínter anal externo: reporte de un caso 2011
- Exclusive nodal recurrence after treatment of degenerated parietal endometriosis 2010
- Clear Cell Adenocarcinoma Arising in Endometriosis of a Previous Episiotomy Site 2008
- Malignant degeneration of perineal endometriosis in episiotomy scar, case report and review of the literature 2007
- Malignant degeneration of perineal endometriosis in episiotomy scar, case report and review of the literature 2007
- Endoanal ultrasonography in the diagnosis and operative management of perianal endometriosis: report of two cases 2006
- Mixed Clear Cell and Endometrioid Carcinoma Arising in Parietal Endometriosis 2006
- The Obstetrical History in Patients with Pfannenstiel Scar Endometriomas – An Analysis of 81 Patients 2006
- Laparoscopic management of vaginal clear cell adenocarcinoma arising in pelvic endometriosis: Case report and literature review 2006
- Operative Therapie 2004
Source provenance
- europepmc
- last seen: 2026-07-27T06:15:28.040536+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:13:30.513821+00:00
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