Laparoscopic management of vaginal clear cell adenocarcinoma arising in pelvic endometriosis: Case report and literature review

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This case report details the laparoscopic management of vaginal clear cell adenocarcinoma originating from pelvic endometriosis and reviews relevant literature on the topic.

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Abstract

Vaginal clear cell adenocarcinoma arising from pelvic endometriosis has not been reported in the literature. We report a case of a 50-year-old woman with stage I clear cell adenocarcinoma of the vagina who was found to have endometriosis adjacent to the vaginal tumor. She was treated with neoadjuvant chemoradiation, laparoscopically assisted radical vaginal hysterectomy, radical upper vaginectomy, and pelvic lymphadenectomy followed by combination chemotherapy.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma, Clear Cell Endometriosis Endometriosis Vaginal Neoplasms Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Combined Modality Therapy Endometriosis Female Gynecologic Surgical Procedures Humans Laparoscopy Middle Aged Neoplasm Staging Pelvis Vaginal Neoplasms Vaginal Neoplasms Vaginal Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (31)

Cited by (2)

Source provenance

europepmc
last seen: 2026-09-15T06:16:59.523076+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
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License: CC0 · commercial use OK