Diagnosis and treatment of perineal endometriosis: review of 17 cases

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This retrospective review of 17 cases demonstrates that perineal endometriosis, diagnosed via detailed history, physical exam, and ultrasound, is effectively treated with complete surgical excision.

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Abstract

PurposeTo demonstrate the appropriate diagnosis and treatment of perineal endometriosis.MethodsSeventeen patients who presented with a tender perineal mass coinciding with the menstrual cycle on the scar of a previous vaginally procedure were examined retrospectively. Their clinical features and treatment were analyzed.ResultsAll patients presented with a palpable painful lesion. All of them had had vaginal delivery with episiotomy. The mean age of the patients was 34.35 years. The mean latent period was 46.82 months. The mean size was 2.38 cm. Thirteen patients presented with one subcutaneous nodule and four had multiple nodules. Color Doppler ultrasound revealed a subcutaneous nodule with an irregular outline and echo-complex density underlying the episiotomy scar. Only one patient suffered from perineal endometriosis combined with pelvic endometriosis. All endometriotic masses in perineum were completely excised and cured, and confirmed by the microscopic examination.ConclusionsA detailed history and thorough pelvic examination are essential in diagnosing perineal endometriosis. Surgical intervention is the first choice of treatment.
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Abstract

Purpose To demonstrate the appropriate diagnosis and treatment of perineal endometriosis.

Methods

Seventeen patients who presented with a tender perineal mass coinciding with the menstrual cycle on the scar of a previous vaginally procedure were examined retrospectively. Their clinical features and treatment were analyzed.

Results

All patients presented with a palpable painful lesion. All of them had had vaginal delivery with episiotomy. The mean age of the patients was 34.35 years. The mean latent period was 46.82 months. The mean size was 2.38 cm. Thirteen patients presented with one subcutaneous nodule and four had multiple nodules. Color Doppler ultrasound revealed a subcutaneous nodule with an irregular outline and echo-complex density underlying the episiotomy scar. Only one patient suffered from perineal endometriosis combined with pelvic endometriosis. All endometriotic masses in perineum were completely excised and cured, and confirmed by the microscopic examination.

Conclusions

A detailed history and thorough pelvic examination are essential in diagnosing perineal endometriosis. Surgical intervention is the first choice of treatment. Similar content being viewed by others

References

Giudice LC, Kao LC (2004) Endometriosis. Lancet 364:1789–1799 Cai SQ, Zheng M, Man XY (2014) Perineal endometriosis: a case report. Int J Clin Exp Med 7:2939–2940 Buda A, Ferrari L, Marra C, Passoni P, Perego P, Milani R (2008) Vulvar endometriosis in surgical scar after excision of the Bartholin gland: report of a case. Arch Gynecol Obstet 277:255–256 Nasu K, Okamoto M, Nishida M, Narahara H (2013) Endometriosis of the perineum. J Obstet Gynecol Res 39:1095–1097 Zhu L, Lang J, Wang H, Liu Z, Sun D, Leng J, Zhou H, Cui Q, Wong F (2009) Presentation and management of perineal endometriosis. Int J Gynaecol Obstet 105:230–232 Watanabe M, Kamiyama G, Yamazaki K, Hiratsuka K, Takata M, Tsunoda A, Shibusawa M, Kusano M (2003) Anal endosonography in the diagnosis and management of perineal endometriosis: report of a case. Surg Today 33:630–632 Gunes M, Kayikcioglu F, Ozturkogu E, Haberal A (2005) Incisional endometriosis after cesarean section, episiotomy and other gynecologic procedures. J Obstet Gynaecol Res 31:471–475 Audebert AJ (1990) External endometriosis: histogenesis, etiology and natural course. Rev Prat 40:1077–1081 Haley JC, Mirowski GW, Hood AF (1998) Benign vulvar tumors. Semin Cutan Med Surg 17:196–204 Cinardi N, Franco S, Centonze D, Giannone G (2011) Perineal scar endometriosis ten years after Mile’s procedure for rectal cancer: case report and review of the literature. Int J Surg Case Rep 2:150–153 Dragoumis K, Mikos T, Zafrakas M, Assimakopoulos E, Stamatopoulos P, Bontis J (2004) Endometriotic uterocutaneous fistula after cesarean section. Gynacol Obstet Invest 57:90–92 Savelli L, Manuzzi L, Di Donato N, Salfi N, Trivella G, Ceccaroni M, Seracchioli R (2012) Endometriosis of the abdominal wall: ultrasonographic and Doppler characteristics. Ultrasound Obstet Gynecol 39:336–340 Zorbas KA, Economopoulos KP, Vlahos NF (2015) Continuous versus cyclic oral contraceptives for the treatment of endometriosis: a systematic review. Arch Gynecol Obstet. doi:10.1007/s00404-015-3641-1 Andres MP, Lopes LA, Baracat EC, Podgaec S (2015) Dienogest in the treatment of endometriosis: systematic review. Arch Gynecol Obstet. doi:10.1007/s00404-015-3681-6 Chene G, Darcha C, Dechelotte P, Mage G, Canis M (2007) Malignant degeneration of perineal endometriosis in episiotomy scar, case report and review of the literature. Int J Gynecol Cancer 17:709–714 Conflict of interest All authors declare no conflict of interests and funding in the manuscript, including financial, consultant, institutional and other relationships that might lead to bias. Ethical standards The manuscript does not contain clinical studies or patient data. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Li, J., Shi, Y., Zhou, C. et al. Diagnosis and treatment of perineal endometriosis: review of 17 cases. Arch Gynecol Obstet 292, 1295–1299 (2015). https://doi.org/10.1007/s00404-015-3756-4 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00404-015-3756-4

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Episiotomy Perineum Adult Cicatrix Cicatrix Endometriosis Endometriosis Endometriosis Episiotomy Female Humans Incidence Menstrual Cycle Pain Pain Perineum Perineum Pregnancy Retrospective Studies

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