Characteristics and long-term outcomes of perineal endometriosis

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AI-generated summary by claude@2026-06, 2026-06-07

This retrospective study characterized perineal endometriosis, finding it often presents as painful vulvar swellings related to menstruation, frequently on episiotomy scars, and determined that complete surgical excision is necessary while investigating the recurrence rates between GnRH agonist and non-GnRH agonist treatment groups.

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Abstract

To summarize the clinical features, diagnosis, and treatments of perineal endometriosis (PEM).We retrospectively studied the clinical data of 35 patients with PEM between April 2012 and December 2018 in West China Second Hospital. Patients were divided into the gonadotropins releasing hormone (GnRH) agonist group and non-GnRH agonist group.The main clinical symptom was vulvar painful swellings related to menstrual cycles. Thirty-three patients' lesions (94.29%) were on the episiotomy scar while 1 case was at the opposite side of the scar. We even found 1 nullipara was diagnosed as PEM. Ten patients (28.57%) were found with anal sphincter involvement. All patients received complete excision of PEM. The recurrence rate of GnRH agonist group was 7.69% (1/13), while the rate of non-GnRH agonist group was 18.75% (3/16).Most PEM was associated with episiotomy history, but PEM could also exist in nullipara. Complete excision of PEM was inevitable. The effect of GnRH agonist on recurrence of PEM needs further studies.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Episiotomy Adult Case-Control Studies Endometriosis Endometriosis Endometriosis Episiotomy Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Humans Menstrual Cycle Menstrual Cycle Middle Aged Parity Perineum Perineum Pregnancy Retrospective Studies

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References (19)

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europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:21:59.141895+00:00
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