Primary vulvar endometriosis in postmenopausal woman: a case report and review of the literature

Giuseppe Sarpietro, Sarpietro G, Maria G Matarazzo, Maria Grazia Matarazzo, Matarazzo MG, Vecchio GM, Giada Maria Vecchio, Giada M Vecchio, Gaia Palermo, Palermo G, Cianci A, Antonio Cianci
Minerva obstetrics and gynecology · 2023 · vol. 75(4) , pp. 387–389 · doi:10.23736/s2724-606x.22.05089-8 · PMID:37458252 · W4384563850
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This case report describes a rare instance of primary vulvar endometriosis in an 84-year-old postmenopausal woman, highlighting the diagnostic challenges and the need for surgical excision for confirmation.

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Abstract

Endometriosis is a benign, estrogen-dependent condition that commonly affects women during the reproductive age. Postmenopausal endometriosis is a rare condition because of the absence of estrogenic hormone production. Furthermore, extrapelvic endometriosis is a rare and complex phenomenon. For this reason, it is usually a misdiagnosed disease. An 84-year-old female patient with no medical history of endometriosis or dysmenorrhea and no hormone replacement therapy was found to have a 4.4×3 cm tender, mobile mass on the left labium majus detached from the underlying perineal muscle. The patient underwent surgical excision under sedation and local anesthesia. The mass was easily removed intact and was not adherent to the vagina or the perineal muscles. Surgical resection of the lesion should be performed in order to remove the lesion and to confirm the diagnosis histologically. The diagnosis of long-standing endometriotic cyst was made. Primary vulvo-perineal endometriosis is a rare and difficult diagnosis especially in postmenopausal women without previous surgical procedures and no history of endometriosis. A better awareness of symptoms and signs of uncommon locations of extrapelvic endometriosis should be encouraged in order to optimize patient care. Finally, more research is needed to elucidate the pathogenesis of endometriosis in postmenopausal women.

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Condition tags

endometriosisdysmenorrhea

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (12)

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License: CC0 · commercial use OK