Association between chronic pelvic pain symptoms and the presence of endometriosis

article OA: closed CC0 ⤵ 50 in-corpus citations
AI-generated summary by claude@2026-06+body, 2026-06-12

This study investigated the relationship between chronic pelvic pain and endometriosis severity, finding laparoscopic treatment improved symptoms but the overall association between endometriosis stage and symptom severity was marginal.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text

This prospective observational study assessed 144 women with chronic pelvic pain who underwent laparoscopy to evaluate the presence and severity (stage and location) of endometriosis, using 10-point visual analog scale ratings and follow-up of 6 months after laparoscopic treatment. Pain outcomes showed no overall difference in pain intensity between women with and without endometriosis, although advanced endometriosis correlated with dysmenorrhea and specific deep or rectovaginal disease locations were associated with dyspareunia or dyschezia. The authors note that the overall association between endometriosis presence/stage and severity of symptoms was marginal. Laparoscopic treatment improved symptoms during follow-up. This paper is centrally about endometriosis — it examines how chronic pelvic pain symptoms relate to the presence, stage, and anatomic location of endometriosis.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Full text 8,137 characters · extracted from oa-doi-fallback · 5 sections · click to expand

Abstract

Purpose The link between endometriosis and the presence or intensity of pain is controversial. The aim of the present study was to assess the relationship between chronic pelvic pain (CPP) and severity of endometriosis and the effectiveness of laparoscopic treatment in a 6-month follow-up.

Methods

Prospective observational study in a referral unit. 144 women had laparoscopy to investigate CPP. Symptoms were assessed by a 10-point visual analog scale. The main outcome measure was the frequency and intensity of CPP.

Results

No difference in pain was found between women with and without endometriosis. Advanced endometriosis was associated with dysmenorrhea, deep endometriosis with dyspareunia and rectovaginal disease with dyschezia. Laparoscopic treatment improves symptoms.

Conclusions

Women with severe endometriosis are more likely to report severe dysmenorrhoea. Furthermore location of endometriosis in the rectovaginal space is associated with dyschezia and deep endometriosis with dyspareunia. However, the association between presence and stage of endometriosis and severity of symptoms is marginal. Similar content being viewed by others

References

Ballard K, Seaman H, de Vries C, Wright J (2008) Can symptomatology help in the diagnosis of endometriosis? Findings from a national case control study. Part 1. Br J Obstet Gynaecol 115:1382–1391 Moen MH, Muus KM (1991) Endometriosis in pregnant and non-pregnant women at tubal sterilization. Hum Reprod 6:699–702 Howard FM (1993) The role of laparoscopy in chronic pelvic pain: promise and pitfalls. Obstet Gynecol Surv 48:357–387 The American Fertility Society (1985) Revised American fertility society classification of endometriosis. Fertil Steril 43:351–352 Brosens I, Donnez J, Benagiano G (1993) Improving the classification of endometriosis. Hum Reprod 8:1792–1795 Abbott JA, Hawe J, Clayton RD, Garry R (2003) The effects and effectiveness of laparoscopic excision of endometriosis: a prospective study with 2–5 year follow-up. Hum Reprod 18:1922–1927 Wright J, Lotfallah H, Jones K, Lovell D (2005) A randomized trial of excision versus ablation for mild endometriosis. Fertil Steril 83:1830–1836 Healey M, Cheng C, Kaur H (2014) To excise or ablate endometriosis? A prospective randomized double-blinded trial after 5-year follow-up. J Minim Invasive Gynecol 21(6):999–1004 Wykes C, Clark T, Khan K (2004) Accuracy of laparoscopy in the diagnosis of endometriosis: a systematic quantitative review. BJOG 111:1204–1212 Shafik A, Ratcliffe N, Wright J (2000) The importance of histological diagnosis in patients with chronic pelvic pain and laparoscopic evidence of endometriosis. Gynaecol Endosc 9:301–304 Chopin N, Vieira M, Borghese B, Foulot H, Dousset B, Coste J, Mignon A, Fauconnier A, Chapron C (2005) Operative management of deeply infiltrating endometriosis: results on pelvic pain symptoms according to a surgical classification. J Minim Invasive Gynecol 12:106–112 Banerjee S, Ballard KD, Lovell DP, Wright J (2006) Deep and superficial endometriotic disease: the response to radical laparoscopic excision in the treatment of chronic pelvic pain. Gynecol Surg 3:199–205 Lukic A, Di Properzio M, De Carlo S, Nobili F, Schimberni M, Bianchi P, Prestigiacomo C, Moscarini M, Caserta D (2015) Quality of sex life in endometriosis patients with deep dyspareunia before and after laparoscopic treatment. Arch Gynecol Obstet. doi:10.1007/s00404-015-3832-9 Ford J, English J, Miles WA, Giannopoulos T (2004) Pain, quality of life and complications following the radical resection of rectovaginal endometriosis. BJOG 111:353–356 Wright JT, Shafik A (2001) Quality of life following radical excision of rectovaginal endometriosis associated with complete obliteration of the posterior cul de sac. Gynaecol Endosc 10:107–110 Garry R, Clayton R, Hawe J (2000) The effect of endometriosis and its radical laparoscopic excision on quality of life indicators. BJOG 107:44–54 Fedele L, Bianchi S, Zanconato G, Bettoni G, Gotsch F (2004) Long-term follow-up after conservative surgery for rectovaginal endometriosis. Am J Obstet Gynecol 190:1020–1024 European Society of Human Reproduction and Embryology (2014) ESHRE guideline: management of women with endometriosis. Hum Reprod 29:400–412 Abbott J, Hawe J, Hunter D, Holmes M, Finn Garry R (2004) Laparoscopic excision of endometriosis: a randomized, placebo-controlled trial. Fertil Steril 82:878–884 Sampson JA (1927) Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity. Am J Obstet Gynecol 14:422–425 Koninckx PR, Meuleman C, Demeyere S, Lesaffre E, Cornillie FJ (1991) Suggestive evidence that pelvic endometriosis is a progressive disease, whereas deeply infiltrating endometriosis is associated with pelvic pain. Fertil Steril 55:759–765 Vercellini P, Fedele L, Aimi G, Pietropaolo G, Consonni D, Crosignani P (2007) Association between endometriosis stage, lesion type, patient characteristics and severity of pelvic pain symptoms: a multivariate analysis of over 1000 patients. Hum Reprod 22:266–271 Haas D, Chvatal R, Reichert B, Renner S, Shebl O, Binder H, Wurm P, Oppelt P (2012) Endometriosis: a premenopausal disease? Age pattern in 42,079 patients with endometriosis. Arch Gynecol Obstet 286:667–670 Vercellini P, Trespidi L, De Giorgi O, Cortesi I, Parazzini F, Crosignani PG (1996) Endometriosis and pelvic pain: relation to disease stage and localization. Fertil Steril 65:299–304 Harrison RF, Barry-Kinsella C (2000) Efficacy of medroxyprogesterone treatment in infertile women with endometriosis: a prospective, randomized, placebo-controlled study. Fertil Steril 74:24–30 Fauconnier A, Chapron C (2005) Endometriosis and pelvic pain: epidemiological evidence of the relationship and implications. Hum Reprod 11:595–606 Popora M, Koninckx P, Piazze J, Natili M, Colagrande S, Cosmi E (1999) Correlation between endometriosis and pelvic pain. J Am Assoc Gynecol Laparosc 6:429–434 Fedele L, Parazzini F, Bianchi S, Arcaini L, Candiani GB (1990) Stage and localization of pelvic endometriosis and pain. Fertil Steril 53:155–158 Fauconnier A, Chapron C, Dubuisson JB, Vieira M, Dousset B, Breart G (2002) Relation between pain symptoms and the anatomic location of deep infiltrating endometriosis. Fertil Steril 78:719–726 Ferrero S, Abbamonte LH, Giordano M, Ragni N, Remorgida V (2007) Deep dyspareunia and sex life after laparoscopic excision of endometriosis. Hum Reprod 22:1142–1148 Gruppo Italiano per lo Studio dell’ Endometriosi (2001) Relationship between stage site and morphological characteristics of pelvic endometriosis and pain. Hum Reprod 16:2668–2671 Duffy JM, Arambage K, Correa FJ, Olive D, Farquhar C, Garry R, Barlow DH, Jacobson TZ (2014) Laparoscopic surgery for endometriosis. Cochrane Database Syst Rev. doi:10.1002/14651858.CD011031.pub2 Ballard K, Lane H, Hudelist G, Banerjee S, Wright J (2010) Can specific pain symptoms help in the diagnosis of endometriosis? A cohort study of women with chronic pelvic pain. Fertil Steril 94:20–27 Ballard KD, Lowton K, Wright J (2006) What’s the delay? A qualitative study of women’s experience of reaching a diagnosis of endometriosis. Fertil Steril 85:1296–1301 Deguara CS, Pepas L, Davis C (2012) Does minimally invasive surgery for endometriosis improve pelvic symptoms and quality of life? Curr Opin Obstet Gynecol 24:241–244 Author information Authors and Affiliations Corresponding author Ethics declarations Conflict of interest All authors declare that they do not they have a financial relationship with the organization that sponsored the research and they confirm to have full control of all primary data and that they agree to allow the Journal to review their data if requested. Rights and permissions About this article Cite this article Apostolopoulos, N.V., Alexandraki, K.I., Gorry, A. et al. Association between chronic pelvic pain symptoms and the presence of endometriosis. Arch Gynecol Obstet 293, 439–445 (2016). https://doi.org/10.1007/s00404-015-3855-2 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00404-015-3855-2

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

dysmenorrheadyspareuniaendometriosischronic_pelvic_pain

MeSH descriptors

Chronic Pain Endometriosis Pelvic Pain Adult Case-Control Studies Chronic Pain Chronic Pain Dysmenorrhea Dysmenorrhea Dysmenorrhea Dysmenorrhea Dyspareunia Dyspareunia Dyspareunia Endometriosis Endometriosis Endometriosis Endometriosis Female Follow-Up Studies

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (36)

Cited by (50)

Source provenance

europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:17:39.907309+00:00
unpaywall
last seen: 2026-06-13T06:42:57.164913+00:00
License: CC0 · commercial use OK