Guideline No. 468: Clinical Management of Endometriosis

Yong PJ, Paul J Yong, Allaire C, Catherine Allaire, Bedaiwy M, Mohamed Bedaiwy, Bougie O, Olga Bougie, Kives S, Sari Kives, Sarah Maheux-Lacroix, Maheux-Lacroix S, Murji A, Ally Murji, Singh SS, Sukhbir S Singh, Baharak Amir, SOGC Clinical Gynaecology Committee (2026), endometriosis management working group, Elsie Amoako, Krisztina Bajzak, Roland Antaki, Dr. Krisztina Bajzak, Philippa Brain, Philippa Bridge-Cook, Nicole Douglas, Lacey Brennan, Devon Evans, Madeleine Lemyre, Aisling Clancy, Mathew Leonardi, Stéphanie Dufour, Stephanie Dufour, Katelyn Luciani, Siddi Mathur, Chelsea Elwood, Marilee Nowgesic, Andréanne Jodoin, Chandrew Rajakumar, Kiel Luhning, Elizabeth Randle, Sarah McQuillan, Kate Wahl, Lindsay Wolfson, Tarek Motan, Nick Leyland, Nigel Pereira, Alice Pham, Frank Potestio, David Rittenberg, Jane Schulz, Susan Thorne, Angela Vinturache, Andrew Zakhari, SOGC Guideline Management Oversight Committee (2026), Christine Bloch, Emmanuel Bujold, Susan Chamberlain, Jocelynn Cook, Diane Francoeur, Bing Guthrie, Kristin Harris, Sarah Healey, Amy Metcalfe, Jessica Papillon-Smith, Vanessa Poliquin, Anita Smith, Bianca Stortini, Karla Willows, R Douglas Wilson, Karen Wong
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2026 · vol. 48(6) , pp. 103382 · doi:10.1016/j.jogc.2026.103382 · PMID:42035991 · W7155540371
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This guideline provides healthcare professionals with evidence-based approaches to manage endometriosis and its symptoms, aiming to reduce pain, improve fertility, and enhance quality of life.

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Abstract

OBJECTIVE: To provide health care professionals with an evidence-based approach to the management of endometriosis and its associated symptoms. TARGET POPULATION: Women and gender-diverse individuals affected by endometriosis. BENEFITS, HARMS, AND COSTS: Timely and effective management of endometriosis has the potential to reduce pain, improve fertility and quality of life, and enhance long-term health outcomes. Early intervention may also help mitigate the financial and health system burdens associated with delayed diagnosis and treatment. EVIDENCE: Published literature was retrieved through searches of PubMed, Ovid, Medline, Embase, Scopus, and the Cochrane Library from August 2010 through December 2025, using relevant MeSH heading and keywords. Results were restricted to systematic reviews, meta-analyses, randomized controlled trials/controlled clinical trials, observational studies, and clinical practice guidelines. Results were limited to English or French language materials. Evidence was supplemented with references from the 2010 Society of Obstetricians and Gynaecologists of Canada guideline No. 244. VALIDATION METHODS: The authors rated the quality of evidence and strength of recommendations using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. See online Appendix A (Tables A1 for definitions and A2 for interpretations of strong and conditional recommendations). INTENDED AUDIENCE: Health care providers involved in the care of individuals with endometriosis. SOCIAL MEDIA ABSTRACT: Early identification and management of endometriosis can significantly improve patient outcomes, reduce long-term health care costs and improve their quality of life. SUMMARY STATEMENTS: RECOMMENDATIONS.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

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