Guideline No. 437: Diagnosis and Management of Adenomyosis

E Shirin Dason; Madalina Maxim; Ari P. Sanders; Ari Sanders; Jessica Papillon-Smith; Jessica Papillon‐Smith; Danny Siu‐Chun Ng; Danny Ng; Crystal Chan; Mara Sobel

doi:10.1016/j.jogc.2023.04.008

Guideline No. 437: Diagnosis and Management of Adenomyosis

E Shirin Dason, Madalina Maxim, Ari P. Sanders, Ari Sanders, Jessica Papillon-Smith, Jessica Papillon‐Smith, Danny Siu‐Chun Ng, Danny Ng, Crystal Chan, Mara Sobel

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2023 · vol. 45(6) , pp. 417–429.e1 · doi:10.1016/j.jogc.2023.04.008 · PMID:37244746 · W4378190119

article OA: closed CC0 ⤵ 36 in-corpus citations

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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This guideline outlines diagnostic methods and management strategies for adenomyosis, addressing its clinical presentation and treatment options.

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Condition tags

mesh:D017699adenomyosis

MeSH descriptors

Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (69)

Adenomyosis and in vitro fertilization impacts - A literature review via openalex
Adenomyosis in infertile women: prevalence and the role of 3D ultrasound as a marker of severity of the disease via openalex
Association between ultrasound features of adenomyosis and severity of menstrual pain via openalex
A Systematic Review of Adenomyosis: It Is Time to Reassess What We Thought We Knew about the Disease via openalex
A Systematic Review of Tissue Sampling Techniques for the Diagnosis of Adenomyosis via openalex
Classification and Reporting Systems for Adenomyosis via openalex
Comparison of dienogest versus combined oral contraceptive pills in the treatment of women with adenomyosis: A randomized clinical trial via openalex
Comparison of levonorgestrel intrauterine system versus hysterectomy on efficacy and quality of life in patients with adenomyosis via openalex
Current and Future Surgical and Interventional Management Options for Adenomyosis via openalex
Current diagnosis and management of adenomyosis in Canada: A survey of Canadian gynaecologists via openalex
Development of a clinical prediction model for diagnosing adenomyosis via openalex
Does presence of adenomyosis affect reproductive outcome in IVF cycles? A retrospective analysis of 973 patients via openalex
Effect of pretreatment with a levonorgestrel-releasing intrauterine system on IVF and vitrified–warmed embryo transfer outcomes in women with adenomyosis via openalex
Efficacy of hormonal therapies for decreasing uterine volume in patients with adenomyosis via openalex
Efficacy of long-term, low-dose gonadotropin-releasing hormone agonist therapy (draw-back therapy) for adenomyosis. via openalex
Efficacy of the levonorgestrel-releasing intrauterine device is associated with different subtypes of adenomyosis: a retrospective study via openalex
Evaluating the safety of dienogest in women with adenomyosis: A retrospective analysis via openalex
Evaluation of NovaSure® global endometrial ablation in symptomatic adenomyosis: A longitudinal study with a 36 month follow-up via openalex
Gonadotropin-releasing hormone antagonist (linzagolix): a new therapy for uterine adenomyosis via openalex
How common is adenomyosis? A prospective study of prevalence using transvaginal ultrasound in a gynaecology clinic via openalex
Is adenomyosis associated with menorrhagia? via openalex
Laparoscopy-guided myometrial biopsy in the definite diagnosis of diffuse adenomyosis via openalex
Levonorgestrel-releasing intrauterine system versus a low-dose combined oral contraceptive for treatment of adenomyotic uteri: a randomized clinical trial via openalex
Long‐term dienogest administration in patients with symptomatic adenomyosis via openalex
Long-term efficacy and feasibility of levonorgestrel-releasing intrauterine device use in patients with adenomyosis via openalex
Long-Term Follow-up of Uterine Artery Embolization for Symptomatic Adenomyosis via openalex
Long-term pituitary downregulation before frozen embryo transfer could improve pregnancy outcomes in women with adenomyosis via openalex
Long-Term Vaginal Danazol Treatment in Fertile Age Women with Adenomyosis via openalex
No. 292-Abnormal Uterine Bleeding in Pre-Menopausal Women via openalex
Norethindrone Acetate in the Medical Management of Adenomyosis via openalex
Objective measures of adenomyosis on MRI and their diagnostic accuracy—a systematic review & meta‐analysis via openalex
Outcomes in Adenomyosis Treated with Uterine Artery Embolization Are Associated with Lesion Vascularity: A Long-Term Follow-Up Study of 252 Cases via openalex
Pregnancy outcomes with donor oocyte embryos in patients diagnosed with adenomyosis using the Morphological Uterus Sonographic Assessment criteria via openalex
Pregnancy rate in women with adenomyosis undergoing fresh or frozen embryo transfer cycles following gonadotropin-releasing hormone agonist treatment via openalex
Question Mark Sign and Transvaginal Ultrasound Uterine Tenderness for the Diagnosis of Adenomyosis via openalex
Recurrence of uterine adenomyosis after administration of gonadotropin-releasing hormone agonist and the efficacy of dienogest via openalex
Role of transvaginal sonography and magnetic resonance imaging in the diagnosis of uterine adenomyosis via openalex
Sonographic classification and reporting system for diagnosing adenomyosis via openalex
Symptoms and classification of uterine adenomyosis, including the place of hysteroscopy in diagnosis via openalex
The impact of adenomyosis on IVF outcomes: a prospective cohort study via openalex
The impact of adenomyosis on the outcome of IVF–embryo transfer via openalex
The rate of euploid miscarriage is increased in the setting of adenomyosis via openalex
[The second generation endometrial ablation (NovaSure) improves efficacy of levonorgestrel-releasing intrauterine system in management of adenomyosis]. via openalex
Transvaginal sonographic features of diffuse adenomyosis in 18–30‐year‐old nulligravid women without endometriosis: association with symptoms via openalex
Transvaginal Ultrasound for the Diagnosis of Adenomyosis: Systematic Review and Meta-Analysis via openalex
Treatment of symptomatic adenomyosis with the levonorgestrel‐releasing intrauterine system via openalex
Ulipristal acetate use in adenomyosis: A randomized controlled trial via openalex
Ultrasound scan and magnetic resonance imaging for the diagnosis of adenomyosis: systematic review comparing test accuracy via openalex
Uterine adenomyosis and adenomyoma: the surgical approach via openalex
Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis via openalex
Uterine Artery Embolization for the Treatment of Adenomyosis: A Systematic Review and Meta-Analysis via openalex
Uterine Artery Embolization Versus Hysterectomy in the Treatment of Symptomatic Adenomyosis: Protocol for the Randomized QUESTA Trial via openalex
Uterine involvement by endometriosis: Sonographic features from elusive findings to apparent adenomyosis via openalex
W6810748137 via openalex
W2921100324 via openalex
W2922267617 via openalex
W1925466818 via openalex
W2997726328 via openalex
W3077997576 via openalex
W3091709476 via openalex
W2790094279 via openalex
W2753073405 via openalex
W3169942724 via openalex
W3192348819 via openalex
W2167466747 via openalex
W6688370089 via openalex
W6768427268 via openalex
W6778683784 via openalex
W6785127326 via openalex

Cited by (36)

Source provenance

europepmc: last seen: 2026-06-04T01:30:01.192114+00:00
openalex: last seen: 2026-06-10T17:14:06.276822+00:00
pubmed: last seen: 2026-06-04T00:33:50.911596+00:00

License: CC0 · commercial use OK

[1] Adenomyosis and in vitro fertilization impacts - A literature review via openalex

[2] Adenomyosis in infertile women: prevalence and the role of 3D ultrasound as a marker of severity of the disease via openalex

[3] Association between ultrasound features of adenomyosis and severity of menstrual pain via openalex

[4] A Systematic Review of Adenomyosis: It Is Time to Reassess What We Thought We Knew about the Disease via openalex

[5] A Systematic Review of Tissue Sampling Techniques for the Diagnosis of Adenomyosis via openalex

[6] Classification and Reporting Systems for Adenomyosis via openalex

[7] Comparison of dienogest versus combined oral contraceptive pills in the treatment of women with adenomyosis: A randomized clinical trial via openalex

[8] Comparison of levonorgestrel intrauterine system versus hysterectomy on efficacy and quality of life in patients with adenomyosis via openalex

[9] Current and Future Surgical and Interventional Management Options for Adenomyosis via openalex

[10] Current diagnosis and management of adenomyosis in Canada: A survey of Canadian gynaecologists via openalex

[11] Development of a clinical prediction model for diagnosing adenomyosis via openalex

[12] Does presence of adenomyosis affect reproductive outcome in IVF cycles? A retrospective analysis of 973 patients via openalex

[13] Effect of pretreatment with a levonorgestrel-releasing intrauterine system on IVF and vitrified–warmed embryo transfer outcomes in women with adenomyosis via openalex

[14] Efficacy of hormonal therapies for decreasing uterine volume in patients with adenomyosis via openalex

[15] Efficacy of long-term, low-dose gonadotropin-releasing hormone agonist therapy (draw-back therapy) for adenomyosis. via openalex

[16] Efficacy of the levonorgestrel-releasing intrauterine device is associated with different subtypes of adenomyosis: a retrospective study via openalex

[17] Evaluating the safety of dienogest in women with adenomyosis: A retrospective analysis via openalex

[18] Evaluation of NovaSure® global endometrial ablation in symptomatic adenomyosis: A longitudinal study with a 36 month follow-up via openalex

[19] Gonadotropin-releasing hormone antagonist (linzagolix): a new therapy for uterine adenomyosis via openalex

[20] How common is adenomyosis? A prospective study of prevalence using transvaginal ultrasound in a gynaecology clinic via openalex

[21] Is adenomyosis associated with menorrhagia? via openalex

[22] Laparoscopy-guided myometrial biopsy in the definite diagnosis of diffuse adenomyosis via openalex

[23] Levonorgestrel-releasing intrauterine system versus a low-dose combined oral contraceptive for treatment of adenomyotic uteri: a randomized clinical trial via openalex

[24] Long‐term dienogest administration in patients with symptomatic adenomyosis via openalex

[25] Long-term efficacy and feasibility of levonorgestrel-releasing intrauterine device use in patients with adenomyosis via openalex

[26] Long-Term Follow-up of Uterine Artery Embolization for Symptomatic Adenomyosis via openalex

[27] Long-term pituitary downregulation before frozen embryo transfer could improve pregnancy outcomes in women with adenomyosis via openalex

[28] Long-Term Vaginal Danazol Treatment in Fertile Age Women with Adenomyosis via openalex

[29] No. 292-Abnormal Uterine Bleeding in Pre-Menopausal Women via openalex

[30] Norethindrone Acetate in the Medical Management of Adenomyosis via openalex

[31] Objective measures of adenomyosis on MRI and their diagnostic accuracy—a systematic review & meta‐analysis via openalex

[32] Outcomes in Adenomyosis Treated with Uterine Artery Embolization Are Associated with Lesion Vascularity: A Long-Term Follow-Up Study of 252 Cases via openalex

[33] Pregnancy outcomes with donor oocyte embryos in patients diagnosed with adenomyosis using the Morphological Uterus Sonographic Assessment criteria via openalex

[34] Pregnancy rate in women with adenomyosis undergoing fresh or frozen embryo transfer cycles following gonadotropin-releasing hormone agonist treatment via openalex

[35] Question Mark Sign and Transvaginal Ultrasound Uterine Tenderness for the Diagnosis of Adenomyosis via openalex

[36] Recurrence of uterine adenomyosis after administration of gonadotropin-releasing hormone agonist and the efficacy of dienogest via openalex

[37] Role of transvaginal sonography and magnetic resonance imaging in the diagnosis of uterine adenomyosis via openalex

[38] Sonographic classification and reporting system for diagnosing adenomyosis via openalex

[39] Symptoms and classification of uterine adenomyosis, including the place of hysteroscopy in diagnosis via openalex

[40] The impact of adenomyosis on IVF outcomes: a prospective cohort study via openalex

[41] The impact of adenomyosis on the outcome of IVF–embryo transfer via openalex

[42] The rate of euploid miscarriage is increased in the setting of adenomyosis via openalex

[43] [The second generation endometrial ablation (NovaSure) improves efficacy of levonorgestrel-releasing intrauterine system in management of adenomyosis]. via openalex

[44] Transvaginal sonographic features of diffuse adenomyosis in 18–30‐year‐old nulligravid women without endometriosis: association with symptoms via openalex

[45] Transvaginal Ultrasound for the Diagnosis of Adenomyosis: Systematic Review and Meta-Analysis via openalex

[46] Treatment of symptomatic adenomyosis with the levonorgestrel‐releasing intrauterine system via openalex

[47] Ulipristal acetate use in adenomyosis: A randomized controlled trial via openalex

[48] Ultrasound scan and magnetic resonance imaging for the diagnosis of adenomyosis: systematic review comparing test accuracy via openalex

[49] Uterine adenomyosis and adenomyoma: the surgical approach via openalex

[50] Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis via openalex

[51] Uterine Artery Embolization for the Treatment of Adenomyosis: A Systematic Review and Meta-Analysis via openalex

[52] Uterine Artery Embolization Versus Hysterectomy in the Treatment of Symptomatic Adenomyosis: Protocol for the Randomized QUESTA Trial via openalex

[53] Uterine involvement by endometriosis: Sonographic features from elusive findings to apparent adenomyosis via openalex

[54] W6810748137 via openalex

[55] W2921100324 via openalex

[56] W2922267617 via openalex

[57] W1925466818 via openalex

[58] W2997726328 via openalex

[59] W3077997576 via openalex

[60] W3091709476 via openalex

[61] W2790094279 via openalex

[62] W2753073405 via openalex

[63] W3169942724 via openalex

[64] W3192348819 via openalex

[65] W2167466747 via openalex

[66] W6688370089 via openalex

[67] W6768427268 via openalex

[68] W6778683784 via openalex

[69] W6785127326 via openalex