[The second generation endometrial ablation (NovaSure) improves efficacy of levonorgestrel-releasing intrauterine system in management of adenomyosis].

Junyao Lou, Lou J, Xiufeng Huang, Huang X, Lifeng Zhang, Zhang L, Ping Xu, Xu P, Zhang X, Xinmei Zhang, Zhengyun Chen, Chen Z
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2019 · vol. 48(2) , pp. 136–141 · doi:10.3785/j.issn.1008-9292.2019.04.03 · PMID:31309750 · PMC8800655 · W2978018598
article OA: green CC0 ⤵ 6 in-corpus citations
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This study found that combining NovaSure endometrial ablation with a levonorgestrel-releasing intrauterine system improved outcomes for patients with adenomyosis compared to the system alone.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text ⓘ

The paper evaluates whether combining second-generation endometrial ablation using NovaSure with a levonorgestrel-releasing intrauterine system improves treatment efficacy for adenomyosis. It reports on patient management outcomes comparing this combined approach against use of the levonorgestrel-releasing intrauterine system alone, focusing on measures of effectiveness (such as symptom-related or uterine response endpoints as presented by the authors). The major limitation is not stated in the provided text excerpt. This paper is centrally about adenomyosis — specifically, it examines whether NovaSure endometrial ablation enhances the efficacy of levonorgestrel-releasing intrauterine system management.

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Abstract

OBJECTIVE: To determine the efficacy of second generation endometrial ablation (NovaSure) combined with levonorgestrel-releasing intrauterine system (Mirena) in the treatment of adenomyosis. METHODS: Clinical data of patients with adenomyosis admitted in Women's Hospital, Zhejiang University School of Medicine from January 2015 to December 2018 were retrospectively analyzed. Among 66 patients, 44 received Mirena placement only (control group) and 22 received Mirena placement and NovaSure treatment (study group). The menstruation blood loss, dysmenorrhea score, uterine size, expulsion rate of Mirena and the patients' satisfaction rate were assessed in two groups. RESULTS: >0.05). CONCLUSIONS: NovaSure can improve the efficacy of Mirena in treatment of adenomyosis.
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Condition tags

dysmenorrheaadenomyosis

MeSH descriptors

Adenomyosis Adenomyosis Endometrial Ablation Techniques Levonorgestrel Levonorgestrel Dysmenorrhea Female Humans Organ Size Retrospective Studies Uterus Uterus

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (17)

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