Zhengyun Chen

ORCID: 0000-0002-2121-0723 · 21 papers in corpus · active 2005-2024

Study types

  • article 18
  • other 2
  • preprint 1

Condition tags

  • endometriosis 14
  • adenomyosis 7
  • infertility 6
  • dysmenorrhea 4
  • chronic_pelvic_pain 1
other 2024
World journal of emergency medicine ·doi:10.5847/wjem.j.1920-8642.2024.080
article 2024
Acta biomaterialia ·doi:10.1016/j.actbio.2024.09.037
article 2022
Journal of minimally invasive gynecology ·doi:10.1016/j.jmig.2022.02.008

A 43-year-old woman was admitted to the hospital with prolonged menstruation after cesarean delivery for 14 years and intermenstrual bleeding for half a year. Magnetic resonance imaging and ultrasonography revealed a mass of 3.3 cm in diame…

article 2022
·doi:10.2139/ssrn.4028530
article 2022
Journal of clinical medicine ·doi:10.3390/jcm11123489

Although many studies show that patients with diffuse adenomyosis who underwent fertility-sparing surgery can have a successful pregnancy, their pregnancy outcomes are still controversial. The objective of this study was to determine long-t…

article 2021
World journal of clinical cases ·doi:10.12998/wjcc.v9.i35.10805

BACKGROUND: Deep endometriosis (DE) is the most aggressive subtype of endometriosis. The diagnosis may be challenging, and no biomarkers that can discriminate women with DE from those without DE have been developed. AIM: To evaluate the rol…

article 2021
Oxidative medicine and cellular longevity ·doi:10.1155/2021/9979953

Endometriosis is an estrogen‐dependent chronic inflammatory disease that affects approximately 10% of women of reproductive age and up to 50% of women with infertility. The heterogeneity of the disease makes accurate diagnosis and treatment…

article 2021
Drug design, development and therapy ·doi:10.2147/dddt.s323790

INTRODUCTION: Endometriosis (EMs) is associated with severe chronic pelvic pain and infertility and the development of improved EMs treatment options is an ongoing focus. In this study, we investigated the effects of resveratrol on EMs and …

article 2020
World journal of clinical cases ·doi:10.12998/wjcc.v8.i1.188

BACKGROUND: A cystic lesion arising from the myometrium of the uterus, termed as cystic adenomyosis, has chocolate-like, thick viscous contents and contains various amounts of endometrial stroma below the glandular epithelium. It is an extr…

article 2020
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences ·doi:10.3785/j.issn.1008-9292.2020.12.14

The pathogenesis of endometriosis is not well understood at the moment, and the lack of effective biomarkers often leads to delayed diagnosis of the disease. Lipidomics provides a new approach for the diagnosis and prediction of endometrios…

preprint 2020
·doi:10.21203/rs.3.rs-110546/v1
article 2019
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences ·doi:10.3785/j.issn.1008-9292.2019.04.02

OBJECTIVE: To evaluate the efficacy and adverse effects of levonorgestrel-releasing intrauterine system (Mirena) in the treatment of adenomyosis. METHODS: The clinical data of 75 patients with adenomyosis who had Mirena insertion in Women's…

article 2019
Medicine ·doi:10.1097/md.0000000000016965

This study presents the postoperative pregnancy rate of women with recurrent endometriosis and evaluates the predictive value of the endometriosis fertility index (EFI) for the pregnancy.A total of 107 women who wished to conceive after sur…

article 2019
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences ·doi:10.3785/j.issn.1008-9292.2019.04.04

Drug therapy plays an important role in alleviating the symptoms related to adenomyosis, improving the curative effect of surgery, delaying the progress of disease and promoting assisted reproduction. Non-steroidal anti-inflammatory drugs (…

article 2019
·doi:10.4103/2096-2924.268154

Endometriosis (EMS) is a common gynecological disorder characterized by the presence of endometrial tissue outside the uterine cavity. It is commonly associated with pelvic pain and infertility. The exact pathogenesis remains unclear and ma…

article 2019
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences ·doi:10.3785/j.issn.1008-9292.2019.04.03

OBJECTIVE: To determine the efficacy of second generation endometrial ablation (NovaSure) combined with levonorgestrel-releasing intrauterine system (Mirena) in the treatment of adenomyosis. METHODS: Clinical data of patients with adenomyos…

article 2017
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117732161
article 2016
article 2005
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences ·doi:10.3785/j.issn.1008-9292.2005.03.014

OBJECTIVE: To investigate the role of interleukine-16 (IL-16) in the pathogenesis of endometriosis. METHODS: Enzyme-linked immunosorbent assay (ELISA) was used to determine the levels of IL-16 in peritoneal fluid and serum specimens of 22 w…

other 2005
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/j.0001-6349.2005.00679.x
article 2005
·doi:10.1080/j.0001-6349.2005.00679.x

Interleukin-16 (IL-16) is a homotetramer of 14-kDa subunits discovered in 1982 as a T-cell-specific chemoattractant factor. The gene of IL-16 is located on chromosome 15 (15q26.1) and unrelated to other interleukins or chemokines (1). IL-16…