Long-Term Follow-up of Uterine Artery Embolization for Symptomatic Adenomyosis

A J Smeets, Albert J. Smeets, Robbert J. Nijenhuis, R J Nijenhuis, Peter F. Boekkooi, P F Boekkooi, Harry A.M. Vervest, H A M Vervest, W J van Rooij, P N M Lohle, Paul N.M. Lohle
Cardiovascular and interventional radiology · 2011 · vol. 35(4) , pp. 815–819 · doi:10.1007/s00270-011-0203-1 · PMID:21717251 · W2046280067
article OA: closed CC0 ⤵ 51 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-06 ⓘ

Uterine artery embolization preserved the uterus in most women with adenomyosis, rendering them asymptomatic, with only initial junction zone thickness predicting hysterectomy.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-06 ⓘ

This study followed 40 consecutive women with symptomatic adenomyosis treated with uterine artery embolization (UAE) between 1999 and 2006, assessing junction zone thickness by MRI at baseline and 3 months and capturing long-term symptoms and adverse events using the UFS-QoL questionnaire after a mean follow-up of 65 months. During follow-up, 7/40 (18%) underwent hysterectomy, and among these, junction zone thickness was significantly greater at both baseline and 3-month follow-up, whereas most women with a preserved uterus were asymptomatic. Four patients with preserved uterus had substantial residual symptoms and lower overall quality-of-life scores, and there was no relation between clinical outcome and the presence of additional fibroids. This paper is centrally about endometriosis and/or adenomyosis — it is specifically about adenomyosis treated with UAE and its long-term outcomes, including MRI-based predictors of hysterectomy.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Leiomyoma Uterine Artery Embolization Adenomyosis Adenomyosis Adult Chi-Square Distribution Female Follow-Up Studies Humans Hysterectomy Leiomyoma Magnetic Resonance Imaging Middle Aged Quality of Life Retrospective Studies Surveys and Questionnaires Treatment Outcome Uterine Artery Embolization

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