Madeleine Lemyre

OBJECTIVE: To provide health care professionals with an evidence-based approach to the management of endometriosis and its associated symptoms. TARGET POPULATION: Women and gender-diverse individuals affected by endometriosis. BENEFITS, H…

OBJECTIVES: This study aimed to assess whether the presence of endometriosis and/or adenomyosis on advanced ultrasound accounts for variations in quality of life. Our secondary objective was to examine potential determinants of quality of l…

OBJECTIVES: This study aimed to assess the interobserver reproducibility of the Revised American Society for Reproductive Medicine score (r-ASRM) and the Endometriosis Fertility Index (EFI) in women undergoing a conservative laparoscopy to …

OBJECTIVE: To identify pain phenotypes in patients with endometriosis and investigate their associations with demographics, clinical characteristics, comorbidities and pain-related quality of life (QoL). DESIGN: Cross-sectional, single-cen…

OBJECTIVE: To provide a contemporary approach to the understanding of the impact and methods for the diagnosis of endometriosis in Canada. TARGET POPULATION: Individuals, families, communities, health care providers, and health care admini…

Objective To identify phenotypes of pain in patients with endometriosis and to investigate their associations with predictors and quality of life (QoL). Design Population-based study. Setting A referral university center in Quebec City, Can…

OBJECTIVE: To evaluate the effect of hormonal suppression on fertility when administered to infertile patients or patient wishing to conceive after surgery for endometriosis. DATA SOURCES: A systematic search of MEDLINE, EMBASE, CENTRAL an…

OBJECTIVE: To evaluate the diagnostic accuracy of intraoperative laparoscopic imaging tools in reference to that of histopathology for detecting endometriotic lesions and to compare them with conventional white-light inspection by performin…

OBJECTIVE: This guideline reviews the investigation and treatment of primary dysmenorrhea. INTENDED USERS: Health care providers. TARGET POPULATION: Women and adolescents experiencing menstrual pain for which no underlying cause has been …

CONTEXT: Angiogenesis is required for ectopic endometrial tissue growth. Our previous studies showed that prostaglandin F2α (PGF2α) biosynthetic enzymes and receptor were markedly elevated in endometriotic lesions and that PGF2α is a potent…

Studies have long sought specific cytokines that could characterize endometriosis. Either due to variations between study designs regarding the assessment criteria for the cytokine or to low power resulting from small sample size, no factor…

BACKGROUND AND OBJECTIVE: Ambulatory total laparoscopic hysterectomy (TLH) could lead to significant cost savings, but some fear the effects of what could be premature postsurgical discharge. We sought to estimate the feasibility and safety…

Pelvic inflammation is a hallmark of endometriosis pathogenesis and a major cause of the disease's symptoms. Abnormal immune and inflammatory changes may not only contribute to endometriosis-major symptoms, but also contribute to ectopic en…

BACKGROUND: Hysterosalpingosonography has been suggested as a less invasive alternative to hysterosalpingography for detecting tubal occlusion among subfertile women. We aim to determine the diagnostic accuracy of hysterosalpingosonography …

OBJECTIVE: To investigate prostaglandin (PG) biosynthesis and catabolism pathways in eutopic and ectopic endometrium of women with endometriosis. DESIGN: Retrospective study. SETTING: Human reproduction research laboratory. PATIENT(S): F…

Endometriosis is often associated with a chronic pelvic immuno-inflammatory process, which is closely related to disease pathogenesis and major symptoms. Our studies led to the detection of a marked imbalance between IL-1 and its natural in…

OBJECTIVE: To investigate interleukin (IL) 1 receptor accessory protein (IL1RAcP) expression in the eutopic endometrium of women with endometriosis. DESIGN: Retrospective study. SETTING: Human reproduction research laboratory. PATIENT(S)…

OBJECTIVE: To investigate the coexistence of endometriosis in women presenting with symptomatic leiomyomas. DESIGN: Retrospective study. SETTING: Tertiary university medical center. PATIENT(S): We reviewed the medical records of 131 pati…

PURPOSE: We report the clinical characteristics and the principles of laparoscopic management of ureteral endometriosis at our institution. MATERIALS AND METHODS: We retrospectively reviewed the charts of patients with ureteral endometrios…

BACKGROUND: The diagnosis of septic pelvic thrombophlebitis is frequently one of exclusion; a suspicion should arise when fever fails to respond to standard broad-spectrum antibiotic therapy and defervesces within 48 hours of the addition o…