Identification of multiple and distinct defects in prostaglandin biosynthetic pathways in eutopic and ectopic endometrium of women with endometriosis
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This paper identified multiple, distinct defects in prostaglandin biosynthesis pathways within both eutopic and ectopic endometrial tissues from women diagnosed with endometriosis.
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References (75)
- Advances in the management of endometriosis: an update for clinicians via openalex
- Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis via openalex
- A mid-luteal phase comparison of V76 peritoneal fluid volume and its content of PGF2α and PGE2 in women with minimal stage endometriosis and a normal pelvis via openalex
- Anomalies in the inflammatory response in endometriosis and possible consequences: a review. via openalex
- Aromatase inhibitors and cyclooxygenase-2 (COX-2) inhibitors in endometriosis: New questions—old answers? via openalex
- A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis xenografts via antiangiogenic activity in severe combined immunodeficiency mice via openalex
- Basal and stimulated secretion of cytokines by peritoneal macrophages in women with endometriosis via openalex
- Characterization of Lymphocyte Subpopulations and T Cell Activation In Endometriosis via openalex
- Cyclooxygenase-2 expression in deep endometriosis and matched eutopic endometrium via openalex
- Cyclooxygenase-2 Regulates Survival, Migration, and Invasion of Human Endometriotic Cells through Multiple Mechanisms via openalex
- Differential macrophage infiltration in early and advanced endometriosis and adjacent peritoneum via openalex
- Distinct mechanisms regulate cyclooxygenase-1 and -2 in peritoneal macrophages of women with and without endometriosis via openalex
- Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis via openalex
- Ectopic endometrial cells express high concentrations of interleukin (IL)-8 in vivo regardless of the menstrual cycle phase and respond to oestradiol by up-regulating IL-1-induced IL-8 expression in vitro via openalex
- Endocrine and inflammatory factors and endometriosis-associated infertility in assisted reproduction techniques via openalex
- Endocrine Regulation of Menstruation via openalex
- Endometriosis via openalex
- Endometriosis: disease pathophysiology and the role of prostaglandins via openalex
- Endometriosis: Secretion of interleukin-6 by human endometriotic cells and regulation by proinflammatory cytokines and sex steroids via openalex
- Expression of eicosanoid biosynthetic and catabolic enzymes in peritoneal endometriosis via openalex
- Expression of Inducible Microsomal Prostaglandin E Synthase in Local Lesions of Endometriosis Patients via openalex
- Increased Expression of Monocyte Chemotactic Protein-1 in the Endometrium of Women With Endometriosis via openalex
- Macrophage Migration Inhibitory Factor Is Involved in a Positive Feedback Loop Increasing Aromatase Expression in Endometriosis via openalex
- Macrophages and nerve fibres in peritoneal endometriosis via openalex
- Marked elevation of macrophage migration inhibitory factor in the peritoneal fluid of women with endometriosis via openalex
- Metastatic or Embolic Endometriosis, due to the Menstrual Dissemination of Endometrial Tissue into the Venous Circulation. via openalex
- Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis via openalex
- Peritoneal endometriosis is an inflammatory disease via openalex
- Peritoneal endometriosis is an inflammatory disease via openalex
- Peritoneal fluid volume, estrogen, progesterone, prostaglandin, and epidermal growth factor concentrations in patients with and without endometriosis via openalex
- PGE2 and PGF2α release by human peritoneal macrophages in endometriosis via openalex
- Prostaglandin receptor signalling and function in human endometrial pathology via openalex
- Role of cytokines in endometriosis via openalex
- Role of Estrogen Receptor-β in Endometriosis via openalex
- Selective cyclo-oxygenase-2 inhibition induces regression of autologous endometrial grafts by down-regulation of vascular endothelial growth factor-mediated angiogenesis and stimulation of caspase-3-dependent apoptosis via openalex
- Selective Inhibition of Prostaglandin E2 Receptors EP2 and EP4 Induces Apoptosis of Human Endometriotic Cells through Suppression of ERK1/2, AKT, NFκB, and β-Catenin Pathways and Activation of Intrinsic Apoptotic Mechanisms via openalex
- Selective Inhibition of Prostaglandin E2 Receptors EP2 and EP4 Inhibits Adhesion of Human Endometriotic Epithelial and Stromal Cells Through Suppression of Integrin-Mediated Mechanisms1 via openalex
- Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits invasion of human immortalized endometriotic epithelial and stromal cells through suppression of metalloproteinases via openalex
- Suppression of annexin A2 by prostaglandin E2 impairs phagocytic ability of peritoneal macrophages in women with endometriosis via openalex
- The role of prostaglandin E <sub>2</sub> in endometriosis via openalex
- W6828680794 via openalex
- W182700988 via openalex
- W1681346990 via openalex
- W1967641836 via openalex
- W1969169755 via openalex
- W1970676517 via openalex
- W1981263394 via openalex
- W1986315358 via openalex
- W2005650140 via openalex
- W2010174634 via openalex
- W2013079253 via openalex
- W2044204905 via openalex
- W2047648080 via openalex
- W2066549596 via openalex
- W2071716296 via openalex
- W2077641423 via openalex
- W2108787980 via openalex
- W2114722789 via openalex
- W2124419959 via openalex
- W2124961025 via openalex
- W2126279698 via openalex
- W2140246703 via openalex
- W2151398298 via openalex
- W2155438634 via openalex
- W2162392926 via openalex
- W2164373167 via openalex
- W2418067841 via openalex
- W2994377017 via openalex
- W4211081176 via openalex
- W4237504024 via openalex
- W4255996882 via openalex
- W6604186803 via openalex
- W6605969444 via openalex
- W6607384979 via openalex
- W6636368206 via openalex
Cited by (29)
- Molecular Basis of Impaired Decidualization in the Eutopic Endometrium of Endometriosis Patients 2025
- Anti-Müllerian hormone is decreased in women with superficial peritoneal endometriosis and associated with an elevated inflammatory profile 2025
- Progressively Diminished Prostaglandin E2 Signaling in Concordance with Increasing Fibrosis in Ectopic Endometrium 2024
- Endometriosis: cannabidiol therapy for symptom relief 2024
- Endometriosis: recent advances that could accelerate diagnosis and improve care 2024
- m6A methyltransferase METTL3 inhibits endometriosis by regulating alternative splicing of MIR17HG 2022
- Is intracrinology of endometriosis relevant in clinical practice? A systematic review on estrogen metabolism 2022
- Changing prostaglandin E2 (PGE<sub>2</sub>) signaling during lesional progression and exacerbation of endometriosis by inhibition of PGE<sub>2</sub> receptor EP2 and EP4 2021
- Maternal–Fetal Outcomes in Women with Endometriosis and Shared Pathogenic Mechanisms 2021
- Higher fibrotic content of endometriotic lesions is associated with diminished prostaglandin E2 signaling 2021
- Use of selective PGE2 receptor antagonists on human endometriotic stromal cells and peritoneal macrophages 2020
- Aldo-keto reductase 1C3—Assessment as a new target for the treatment of endometriosis 2019
- Cyclooxygenase-2 in Endometriosis 2019
- SULFATION PATHWAYS: Contribution of intracrine oestrogens to the aetiology of endometriosis 2018
- Chronic Niche Inflammation in Endometriosis-Associated Infertility: Current Understanding and Future Therapeutic Strategies 2018
- PTGS2 down-regulation in cumulus cells of infertile women with endometriosis 2017
- Endometrial biomarkers for the non-invasive diagnosis of endometriosis 2016
- Risk factors and biomarkers for the recurrence of ovarian endometrioma: about the immunoreactivity of progesterone receptor isoform B and nuclear factor kappa B 2016
- Recent advances in the understanding of endometriosis: the role of inflammatory mediators in disease pathogenesis and treatment 2016
- Augmented Angiogenic Factors Expression via FP Signaling Pathways in Peritoneal Endometriosis 2016
- Obstetric Outcomes in Chinese Women with Endometriosis 2015
- Naproxen sodium decreases prostaglandins secretion from cultured human endometrial stromal cells modulating metabolizing enzymes mRNA expression 2015
- Pathological functions of hypoxia in endometriosis 2015
- Abnormal Expression of Prostaglandins E2 and F2<i>α</i>Receptors and Transporters in Patients with Endometriosis 2015
- Selective modulation of the prostaglandin F2α pathway markedly impacts on endometriosis progression in a xenograft mouse model 2015
- Macrophage Migration Inhibitory Factor Is Involved in Ectopic Endometrial Tissue Growth and Peritoneal-Endometrial Tissue Interaction In Vivo: A Plausible Link to Endometriosis Development 2014
- Women with endometriosis at first pregnancy have an increased risk of adverse obstetric outcome 2014
- The Endometriotic Tissue Lining the Internal Surface of Endometrioma: Hormonal, Genetic, Epigenetic Status, and Gene Expression Profile 2014
- Expression of AKR1B1, AKR1C3 and other genes of prostaglandin F2α biosynthesis and action in ovarian endometriosis tissue and in model cell lines 2014
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