Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits invasion of human immortalized endometriotic epithelial and stromal cells through suppression of metalloproteinases

JeHoon Lee, Sakhila K Banu, Thenmozhi Subbarao, Anna Starzinski-Powitz, Anna Starzinski‐Powitz, Joe A Arosh
Molecular and cellular endocrinology · 2010 · vol. 332(1-2) , pp. 306–313 · doi:10.1016/j.mce.2010.11.022 · PMID:21111772 · W2041847148
article OA: closed CC0 ⤵ 37 in-corpus citations
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Inhibition of prostaglandin E2 receptors EP2 and EP4 suppresses metalloproteinases, thereby reducing invasion by human immortalized endometriotic epithelial and stromal cells.

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Condition tags

endometriosis

MeSH descriptors

Endometrium Epithelial Cells Matrix Metalloproteinase Inhibitors Receptors, Prostaglandin E, EP2 Subtype Receptors, Prostaglandin E, EP4 Subtype Stromal Cells Cell Movement Cell Movement Cells, Cultured Dinoprostone Dinoprostone Endometriosis Endometriosis Endometriosis Endometrium Epithelial Cells Epithelial Cells Female Humans Receptors, Prostaglandin E, EP2 Subtype

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Cited by (37)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
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License: CC0 · commercial use OK