The Impact of Endometriosis across the Lifespan of Women: Foreseeable Research and Therapeutic Prospects

Claude L. Hughes, C L Hughes, Warren G. Foster, W G Foster, Sanjay K. Agarwal
BioMed research international · 2015 · vol. 2015 , pp. 1–8 · doi:10.1155/2015/158490 · PMID:26064879 · W1589775235
review OA: hybrid CC0 ⤵ 21 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This review discusses the impact of chronic inflammation from endometriosis on women's health across their lifespan and proposes research opportunities for novel biomarkers and therapeutics.

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Abstract

In addition to estrogen dependence, endometriosis is characterized by chronic pelvic inflammation. The impact of the chronic pelvic inflammatory state on other organ systems and women's health is unclear. Endometriosis associated chronic inflammation and potential adverse health effects across the lifespan render it imperative for renewed research vigor into the identification of novel biomarkers of disease and therapeutic options. Herein we propose a number of opportunities for research and development of new therapeutics to address the unmet needs in the treatment of endometriosis per se and its ancillary risks for other diseases in women across the lifespan.

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Condition tags

mesh:D004715mesh:D017699endometriosis

MeSH descriptors

Endometriosis Inflammation Pelvic Pain Women's Health Endometriosis Endometriosis Estrogens Estrogens Female Humans Inflammation Inflammation Pelvic Pain Pelvic Pain Quality of Life

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

Cited by (21)

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License: CC0 · commercial use OK