Aromatase inhibitors and cyclooxygenase-2 (COX-2) inhibitors in endometriosis: New questions—old answers?
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This review questions the efficacy of aromatase inhibitors and COX-2 inhibitors for endometriosis based on existing knowledge.
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References (79)
- Analysis of cyclooxygenase-2 (COX-2) expression in different sites of endometriosis and correlation with clinico-pathological parameters via openalex
- Angiogenic Factors in Endometriosis via openalex
- Apoptosis in endometrial glandular and stromal cells in women with and without endometriosis via openalex
- Aromatase: a key molecule in the pathophysiology of endometriosis and a therapeutic target via openalex
- Aromatase as a Therapeutic Target in Endometriosis via openalex
- Aromatase expression in endometriosis via openalex
- Aromatase expression in endometriosis. via openalex
- Aromatasehemmer - theoretisches Konzept und bisherige Erfahrungen in der Endometriosetherapie via openalex
- COX-2 Inhibitors and Their Role in Gynecology via openalex
- Cyclooxygenase-2 expression in deep endometriosis and matched eutopic endometrium via openalex
- Deficient 17 -Hydroxysteroid Dehydrogenase Type 2 Expression in Endometriosis: Failure to Metabolize 17 -Estradiol via openalex
- Deficient 17β-Hydroxysteroid Dehydrogenase Type 2 Expression in Endometriosis: Failure to Metabolize 17β-Estradiol<sup>1</sup> via openalex
- Detection of aromatase cytochrome P-450 in endometrial biopsy specimens as a diagnostic test for endometriosis via openalex
- Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis via openalex
- DNA microarray analysis of gene expression profiles in deep endometriosis using laser capture microdissection via openalex
- Emerging drugs for endometriosis via openalex
- Endometriose via openalex
- Endometriosis: a dysfunction and disease of the archimetra via openalex
- Endometriosis: the pathophysiology as an estrogen-dependent disease via openalex
- Endometriosis: The Ultimate Hormonal Disease via openalex
- Estrogen production in endometriosis and use of aromatase inhibitors to treat endometriosis. via openalex
- Gonadotropin-releasing hormone agonist and danazol normalize aromatase cytochrome P450 expression in eutopic endometrium from women with endometriosis, adenomyosis, or leiomyomas via openalex
- Gonadotropin-releasing hormone analog repairs reduced endometrial cell apoptosis in endometriosis in vitro via openalex
- High endometrial aromatase P450 mRNA expression is associated with poor IVF outcome via openalex
- Medical Management of Endometriosis: Novel Targets and Approaches towards the Development of Future Treatment Regimes via openalex
- Medikament�se Therapie der Endometriose via openalex
- New medical treatments for endometriosis via openalex
- Peritoneal fluid volume, estrogen, progesterone, prostaglandin, and epidermal growth factor concentrations in patients with and without endometriosis via openalex
- Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis via openalex
- Prostaglandin E2 Stimulates Aromatase Expression in Endometriosis-Derived Stromal Cells via openalex
- Prostaglandin E<sub>2</sub>Stimulates Aromatase Expression in Endometriosis-Derived Stromal Cells<sup>1</sup> via openalex
- Spontaneous Apoptosis of Endometrial Tissue is Impaired in Women with Endometriosis via openalex
- Steroid receptor and aromatase expression in baboon endometriotic lesions via openalex
- Successful treatment of severe endometriosis in two premenopausal women with an aromatase inhibitor via openalex
- The effects of post-surgical administration of goserelin plus anastrozole compared to goserelin alone in patients with severe endometriosis: a prospective randomized trial via openalex
- Treatment of Endometriosis via openalex
- Treatment of endometriosis without aromatase inhibitors via openalex
- Treatment of Severe Postmenopausal Endometriosis With an Aromatase Inhibitor via openalex
- Treatment of severe recurrent endometriosis with an aromatase inhibitor in a young ovariectomised woman via openalex
- Ultrastructural comparison of endometriotic implants and eutopic endometrium via openalex
- Use of estrogen antagonists and aromatase inhibitors in endometriosis. via openalex
- W6717087387 via openalex
- W1886969873 via openalex
- W1965992514 via openalex
- W1967877758 via openalex
- W1969169755 via openalex
- W2000050417 via openalex
- W2001162433 via openalex
- W2003566890 via openalex
- W2023963334 via openalex
- W2029278810 via openalex
- W2039274017 via openalex
- W2047289419 via openalex
- W2052942682 via openalex
- W2070609164 via openalex
- W2074705853 via openalex
- W2078422697 via openalex
- W2092843143 via openalex
- W2097865940 via openalex
- W2111226394 via openalex
- W2114782354 via openalex
- W2116168419 via openalex
- W2128100826 via openalex
- W2143080753 via openalex
- W2145149010 via openalex
- W2153979571 via openalex
- W2155024696 via openalex
- W2157162135 via openalex
- W2158299014 via openalex
- W2159803441 via openalex
- W2163690844 via openalex
- W2322133447 via openalex
- W2409682597 via openalex
- W4211081176 via openalex
- W6639108690 via openalex
- W6663385421 via openalex
- W6713819060 via openalex
- W6714698182 via openalex
- W1648593433 via openalex
Cited by (48)
- Resultados de cirugía resectiva colorrectal por Endometriosis Infiltrante Profunda. 6 años de experiencia. 2024
- Ligustrazine: A Review of Its Role and Mechanism in the Treatment of Obstetrical and Gynecological Diseases 2023
- A comparative study between Dydrogesterone alone and combined with Non-Steroidal Anti-Inflammatory Drugs in the treatment of Mild Endometriosis 2023
- Molecular biomarkers of endometriosis 2021
- Role of inflammation in benign gynecologic disorders: from pathogenesis to novel therapies† 2021
- Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review 2021
- Uncovering Potential Roles of Differentially Expressed Genes, Upstream Regulators, and Canonical Pathways in Endometriosis Using an In Silico Genomics Approach 2020
- FACTORS OF ENDOMETRIAL RECEPTIVITY DOWN-REGULATION IN GENITAL ENDOMETRIOSIS 2020
- Functional Expression of TRP Ion Channels in Endometrial Stromal Cells of Endometriosis Patients 2018
- 6-Shogaol reduces progression of experimental endometriosis<i>in vivo</i>and<i>in vitro via</i>regulation of VGEF and inhibition of COX-2 and PGE2-mediated inflammatory responses 2018
- Bufalin suppresses endometriosis progression by inducing pyroptosis and apoptosis 2018
- The efficacy of selective cyclooxygenase 2 inhibitors in the treatment of genital endometriosis 2018
- The effect of genistein on TGF-β signal, dysregulation of apoptosis, cyclooxygenase-2 pathway, and NF-kB pathway in mice peritoneum of endometriosis model 2017
- Die medikamentöse Therapie der Patientin mit Endometriose 2017
- COX-2 gene promoter DNA methylation status in eutopic and ectopic endometrium of Egyptian women with endometriosis 2015
- The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis 2014
- Combination use of ferulic acid, ligustrazine and tetrahydropalmatine inhibits the growth of ectopic endometrial tissue: A multi-target therapy for endometriosis rats 2014
- Role of Nerve Fibres in Endometriosis 2014
- The role of Lipoxin A4 in endometrial biology and endometriosis 2013
- Regression of Experimentally Induced Endometriosis with a New Selective Cyclooxygenase-2 Enzyme Inhibitor 2013
- Identification of multiple and distinct defects in prostaglandin biosynthetic pathways in eutopic and ectopic endometrium of women with endometriosis 2013
- Endometriosis: A Disease That Remains Enigmatic 2013
- Efficacy of letrozole in treatment of endometriosis-related pain 2013
- Anastrozole and celecoxib for endometriosis treatment, good to keep them apart? 2012
- New trends for the medical treatment of endometriosis 2012
- Anti-angiogenic treatment strategies for the therapy of endometriosis 2012
- Regulación del crecimiento del tejido endometrial en respuesta a nuevas alternativas terapéuticas propuestas para tratar la endometriosis 2012
- Hypoxia induces expression of COX-2 through the homeodomain transcription factor CDX1 and orphan nuclear receptor SHP in human endometrial cells 2011
- Traitement de l’endométriose par les inhibiteurs de l’aromatase : efficacité thérapeutique et conséquences osseuses 2010
- Dienogest, a synthetic progestin, inhibits prostaglandin E2 production and aromatase expression by human endometrial epithelial cells in a spheroid culture system 2010
- Expression of aromatase in endometiosis and its relation to clinical laboratory and surgical parameters 2010
- Selective Inhibition of Prostaglandin E2 Receptors EP2 and EP4 Induces Apoptosis of Human Endometriotic Cells through Suppression of ERK1/2, AKT, NFκB and β-CATENIN Pathways and Activation of Intrinsic Apoptotic Mechanisms 2009
- Involvement of resistance to apoptosis in the pathogenesis of endometriosis. 2009
- Cyclooxygenase-2 expression, Ki-67 labeling index, and perifocal neovascularization in endometriotic lesions 2009
- Selective Inhibition of Prostaglandin E2 Receptors EP2 and EP4 Induces Apoptosis of Human Endometriotic Cells through Suppression of ERK1/2, AKT, NFκB, and β-Catenin Pathways and Activation of Intrinsic Apoptotic Mechanisms 2009
- Newer treatment modalities in endometriosis: systematic review 2009
- Non-contraceptive health benefits of oral contraceptives 2008
- A functional promoter polymorphism in interleukin-10 gene influences susceptibility to endometriosis 2008
- Letrozole stimulates the growth of human endometrial explants cultured in three-dimensional fibrin matrix 2008
- Patientinnenzentrierte Aspekte der Endometriose 2008
- Cyclooxygenase-2 Regulates Survival, Migration, and Invasion of Human Endometriotic Cells through Multiple Mechanisms 2007
- Endometriosis intestinal. Estado actual 2007
- Selective Estrogen-Receptor Modulators and Aromatase Inhibitors: Promising New Medical Therapies for Endometriosis? 2007
- Gene expression profiles and functional characterization of human immortalized endometriotic epithelial and stromal cells 2007
- Expression und Regulation von Enzymen des Östrogenmetabolismus in humanen Endometriumläsionen kultiviert in der Nacktmaus 2007
- Aromatase expression in the eutopic endometrium of myomatous uteri: The influence of the menstrual cycle and oral contraceptive use 2007
- Aromatase expression in endometriotic tissues and its relationship to clinical and analytical findings 2007
- Investigational drugs for endometriosis 2006
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