Cyclooxygenase-2 expression, Ki-67 labeling index, and perifocal neovascularization in endometriotic lesions

Lars‐Christian Horn; Lars-Christian Horn; Bettina Hentschel; A. Meinel; Alexandra Meinel; Henry Alexander; Cornelia Leo

doi:10.1016/j.anndiagpath.2009.08.001

Cyclooxygenase-2 expression, Ki-67 labeling index, and perifocal neovascularization in endometriotic lesions

Lars‐Christian Horn, Lars-Christian Horn, Bettina Hentschel, A. Meinel, Alexandra Meinel, Henry Alexander, Cornelia Leo

Annals of diagnostic pathology · 2009 · vol. 13(6) , pp. 373–377 · doi:10.1016/j.anndiagpath.2009.08.001 · PMID:19917472 · W2046108789

article OA: closed CC0 ⤵ 6 in-corpus citations

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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This study investigated cyclooxygenase-2 expression, Ki-67 labeling index, and perifocal neovascularization within endometriotic lesions to understand their roles in lesion development and proliferation.

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Condition tags

endometriosis

MeSH descriptors

Cyclooxygenase 2 Endometriosis Ki-67 Antigen Neovascularization, Pathologic Cell Proliferation Chi-Square Distribution Cyclooxygenase 2 Endometriosis Endometriosis Female Humans Immunohistochemistry Ki-67 Antigen Neovascularization, Pathologic Ovarian Diseases Ovarian Diseases Ovarian Diseases Peritoneal Diseases Peritoneal Diseases Peritoneal Diseases

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References (33)

Analysis of cyclooxygenase-2 (COX-2) expression in different sites of endometriosis and correlation with clinico-pathological parameters via openalex
Aromatase inhibitors and cyclooxygenase-2 (COX-2) inhibitors in endometriosis: New questions—old answers? via openalex
A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis xenografts via antiangiogenic activity in severe combined immunodeficiency mice via openalex
Cancer risk after a hospital discharge diagnosis of endometriosis via openalex
COX-2 overexpression in peritoneal lesions is correlated with nonmenstrual chronic pelvic pain via openalex
Cyclooxygenase-2 expression is higher in ovarian cancer tissue adjacent to endometriosis than in ovarian cancer without comorbid endometriosis via openalex
Cyclooxygenase-2 Regulates Survival, Migration, and Invasion of Human Endometriotic Cells through Multiple Mechanisms via openalex
Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis via openalex
Effect of the menstrual cycle and oral contraceptives on aromatase and cyclooxygenase-2 expression in adenomyosis via openalex
Expression of cyclooxygenase-2 and vascular endothelial growth factor in ovarian endometriotic cysts and their relationship with angiogenesis via openalex
Expression of Glycodelin and Cyclooxygenase‐2 in Human Endometrial Tissue Following Three‐dimensional Culture via openalex
Malignancy in Endometriosis: Frequency and Comparison of Ovarian and Extraovarian Types via openalex
Regression of endometrial explants in rats treated with the cyclooxygenase-2 inhibitor rofecoxib via openalex
Selective cyclo-oxygenase-2 inhibition induces regression of autologous endometrial grafts by down-regulation of vascular endothelial growth factor-mediated angiogenesis and stimulation of caspase-3-dependent apoptosis via openalex
Suppression of IL-1β-induced COX-2 expression by trichostatin A (TSA) in human endometrial stromal cells via openalex
Tubal and ovarian pathways to pelvic epithelial cancer: a pathological perspective via openalex
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W2039274017 via openalex
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W2013226355 via openalex
W2011102961 via openalex
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W1975992888 via openalex
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Cited by (6)

Source provenance

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License: CC0 · commercial use OK

[1] Analysis of cyclooxygenase-2 (COX-2) expression in different sites of endometriosis and correlation with clinico-pathological parameters via openalex

[2] Aromatase inhibitors and cyclooxygenase-2 (COX-2) inhibitors in endometriosis: New questions—old answers? via openalex

[3] A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis xenografts via antiangiogenic activity in severe combined immunodeficiency mice via openalex

[4] Cancer risk after a hospital discharge diagnosis of endometriosis via openalex

[5] COX-2 overexpression in peritoneal lesions is correlated with nonmenstrual chronic pelvic pain via openalex

[6] Cyclooxygenase-2 expression is higher in ovarian cancer tissue adjacent to endometriosis than in ovarian cancer without comorbid endometriosis via openalex

[7] Cyclooxygenase-2 Regulates Survival, Migration, and Invasion of Human Endometriotic Cells through Multiple Mechanisms via openalex

[8] Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis via openalex

[9] Effect of the menstrual cycle and oral contraceptives on aromatase and cyclooxygenase-2 expression in adenomyosis via openalex

[10] Expression of cyclooxygenase-2 and vascular endothelial growth factor in ovarian endometriotic cysts and their relationship with angiogenesis via openalex

[11] Expression of Glycodelin and Cyclooxygenase‐2 in Human Endometrial Tissue Following Three‐dimensional Culture via openalex

[12] Malignancy in Endometriosis: Frequency and Comparison of Ovarian and Extraovarian Types via openalex

[13] Regression of endometrial explants in rats treated with the cyclooxygenase-2 inhibitor rofecoxib via openalex

[14] Selective cyclo-oxygenase-2 inhibition induces regression of autologous endometrial grafts by down-regulation of vascular endothelial growth factor-mediated angiogenesis and stimulation of caspase-3-dependent apoptosis via openalex

[15] Suppression of IL-1β-induced COX-2 expression by trichostatin A (TSA) in human endometrial stromal cells via openalex

[16] Tubal and ovarian pathways to pelvic epithelial cancer: a pathological perspective via openalex

[17] W2040095832 via openalex

[18] W2083256941 via openalex

[19] W2039274017 via openalex

[20] W2032550082 via openalex

[21] W2013628667 via openalex

[22] W2121334345 via openalex

[23] W2013226355 via openalex

[24] W2011102961 via openalex

[25] W1982444413 via openalex

[26] W1979679896 via openalex

[27] W1975992888 via openalex

[28] W1969169755 via openalex

[29] W2319962899 via openalex

[30] W2412285949 via openalex

[31] W6653742043 via openalex

[32] W2050658186 via openalex

[33] W6715288508 via openalex