Effects of etonogestrel implant on quality of life, sexual function, and pelvic pain in women suffering from endometriosis: results from a multicenter, prospective, observational study

Anna Sansone, Nicoletta De Rosa, Pierluigi Giampaolino, Maurizio Guida, Antonio Simone Laganà, Costantino Di Carlo
Archives of gynecology and obstetrics · 2018 · vol. 298(4) , pp. 731–736 · doi:10.1007/s00404-018-4851-0 · PMID:30074068 · W2887636092
article OA: closed CC0 ⤵ 35 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-06 ⓘ

The etonogestrel implant significantly decreased pelvic pain and improved quality of life and sexual function in women with endometriotic ovarian cysts over 12 months.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-06 ⓘ

This multicenter, prospective observational study enrolled 25 women who requested long-term reversible contraception via an etonogestrel (ENG) implant and had ovarian cysts with ultrasound features of endometrioma plus pelvic pain symptoms. Participants completed baseline and follow-up assessments at 6 and 12 months using VAS ratings for dysmenorrhea, dyspareunia, dyschezia, and dysuria, the SF-36 for quality of life, and the Female Sexual Function Index for sexual function. After ENG implantation, dysmenorrhea and dyspareunia VAS scores decreased significantly at 6 and 12 months, SF-36 domains including bodily pain, general health, vitality, social functioning, and mental health improved by 12 months, and total FSFI scores increased, with improvements in desire, satisfaction, and pain at 6 months and arousal improving only at 12 months; endometrioma-like cyst mean diameters were unchanged at 12 months. The authors did not report randomization or a control group, and the sample size was small. This paper is centrally about endometriosis — it evaluates how an etonogestrel implant affects pelvic pain, quality of life, sexual function, and endometrioma-like cysts in women with suspected endometriosis.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Desogestrel Endometriosis Pelvic Pain Quality of Life Sexual Behavior Adult Desogestrel Drug Implants Endometriosis Endometriosis Female Humans Pelvic Pain Prospective Studies Sexual Behavior

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