Clinical Diagnosis and Early Medical Management for Endometriosis: Consensus from Asian Expert Group

Mee-Ran Kim, Mee‐Ran Kim, Charles Chapron, Thomas Römer, Angela Aguilar, Amphan Chalermchockcharoenkit, Siddharta Chatterjee, Lê Thị Anh Đào, Le Thi Anh Dao, Yoke Fai Fong, Hendy Hendarto, Syarief Taufik Hidayat, Su Yen Khong, Li Ma, Pratap Kumar, Relly Yanuari Primariawan, A Siow, Anthony Siow, Areepan Sophonsritsuk, Ramani Devi Thirunavukarasu, Bui Chi Thuong, Chih‐Feng Yen
Healthcare (Basel, Switzerland) · 2022 · vol. 10(12) , pp. 2515 · doi:10.3390/healthcare10122515 · PMID:36554040 · W4312128028
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This consensus guidance from an Asian expert group details clinical diagnosis of endometriosis through symptom recognition and imaging, recommending individualized medical management with progestins or dienogest as first-line treatments for pelvic pain.

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Abstract

This work provides consensus guidance regarding clinical diagnosis and early medical management of endometriosis within Asia. Clinicians with expertise in endometriosis critically evaluated available evidence on clinical diagnosis and early medical management and their applicability to current clinical practices. Clinical diagnosis should focus on symptom recognition, which can be presumed to be endometriosis without laparoscopic confirmation. Transvaginal sonography can be appropriate for diagnosing pelvic endometriosis in select patients. For early empiric treatment, management of women with clinical presentation suggestive of endometriosis should be individualized and consider presentation and therapeutic need. Medical treatment is recommended to reduce endometriosis-associated pelvic pain for patients with no immediate pregnancy desires. Hormonal treatment can be considered for pelvic pain with a clinical endometriosis diagnosis; progestins are a first-line management option for early medical treatment, with oral progestin-based therapies generally a better option compared with combined oral contraceptives because of their safety profile. Dienogest can be used long-term if needed and a larger evidence base supports dienogest use compared with gonadotropin-releasing hormone agonists (GnRHa) as first-line medical therapy. GnRHa may be considered for first-line therapy in some specific situations or as short-term therapy before dienogest and non-steroidal anti-inflammatory drugs as add-on therapy for endometriosis-associated pelvic pain.

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Condition tags

endometriosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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