Epidemiological characteristics in women with and without endometriosis in the Yale series

Ioannis M Matalliotakis, Ioannis Matalliotakis, Hakan Çakmak, Hakan Cakmak, Yvoni G Fragouli, Yvoni Fragouli, Anastasia G Goumenou, Neal G Mahutte, Neal Mahutte, Aydin Arici, Aydın Arıcı
Archives of gynecology and obstetrics · 2007 · vol. 277(5) , pp. 389–393 · doi:10.1007/s00404-007-0479-1 · PMID:17922285 · W2085322970
article OA: closed CC0 ⤵ 141 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This retrospective study identified lower body weight, alcohol use, early menarche, shorter cycles, heavier periods, and fewer prior pregnancies as risk factors for endometriosis, with pelvic pain and a family history of cancer also associated.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This retrospective case-control study analyzed associations between demographic factors, menstrual/reproductive history, and clinical characteristics among 535 women with laparoscopically or laparotomically confirmed endometriosis and 200 infertile women without endometriosis, using uniformly collected medical-record data and χ² and Mann–Whitney U tests. Women with endometriosis had lower body weight, reported alcohol use more often, showed earlier menarche, shorter cycle length, and heavier menstrual cycles, and experienced pelvic pain (79.1%), dysmenorrhea (70.2%), and dyspareunia (49.5%) at significantly higher frequencies than controls (P < 0.001). Compared with women seeking infertility care without endometriosis, the endometriosis group reported fewer prior pregnancies and fewer elective and ectopic pregnancies, and they were more likely to report a family history of cancer (χ² = 78.2; P < 0.001). The study was limited by its retrospective design and reliance on existing records for exposure and symptom information. This paper is centrally about endometriosis — it characterizes epidemiologic and clinical differences between women with and without endometriosis in the Yale series.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Adolescent Adult Alcohol Drinking Body Mass Index Case-Control Studies Cohort Studies Endometriosis Endometriosis Female Humans Laparoscopy Menstruation Disturbances Menstruation Disturbances Middle Aged Reproductive History Risk Factors

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