Bisphenol A levels in bowel endometrioma diagnosed serums: A case control study

Filiz Ardic, Hümeyra Çelik, Hüseyin Yeşilyurt, Serap Mutlu ÖZÇELİK OTCU
In: Experimental Biomedical Research · 2022 · vol. 5(1) , pp. 38–47 · doi:10.30714/j-ebr.2022173849 · W4205863641
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case-control study found significantly higher serum bisphenol A (BPA) levels in patients with endometrioma compared to controls, with even higher levels observed in those with bowel involvement.

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Abstract

Aim: To investigate the bisphenol A (BPA) levels, which may be a risk factor in the etiology of endometrioma, in patients diagnosed laparoscopically with endometrioma with and without bowel involvement. Method: In the prospective cross-sectional case control study, 47 cases were included in the study, which were admitted to the gynecology and infertility services with and without bowel involvement endometrioma who were operated and diagnosed histopathologically. 43 patients were included in the control group. For serum BPA value, blood samples taken immediately before the operation were studied in laboratory. Patients and controls were compared with controls in terms of serum BPA values. Results: The mean age of the patients was 35 2 in the endometriosis group and 36 2 in the control group which was and not statistically significant. There was no statistical difference between the patient and control groups in terms of menstruation periods. Serum BPA levels were significantly higher in the bowel involvement group compared to the non-bowel involvement group, as the distribution width was higher due to excessive values, and only 5 patients with bowel involvement did not reach statistically significant levels. Serum BPA level was 10841132 ng/L in the endometriosis group and 26999 ng/L in the control group which was statistically significant (p<0,001). Conclusions: BPA levels were showing very wide range especially in the patient group. Serum BPA levels was statistically significantly higher in the endometrioma group compared to the control group. Therefore, in the etiology of endometriosis BPA may take a definite place.

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Condition tags

endometriosisendometriomainfertility

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