Pathophysiology and management of urinary tract endometriosis

Camran Nezhat, Rebecca Falik, Sara McKinney, Louise P King
Nature reviews. Urology · 2017 · vol. 14(6) , pp. 359–372 · doi:10.1038/nrurol.2017.58 · PMID:28467398 · W2610503954
review OA: closed CC0 ⤵ 68 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

Urinary tract endometriosis can lead to silent kidney loss and is best managed with laparoscopic surgery, though treatment varies by lesion type and location.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This paper reviews the pathophysiology and management of urinary tract endometriosis, focusing on endometriotic lesions affecting the ureter and bladder and how extent, depth, and lesion location shape treatment choice. It reports that urinary tract endometriosis is often considered rare but may be underrecognized, and notes that ureteral endometriosis can cause silent kidney loss if not effectively managed. The paper states that hormonal medical approaches (e.g., GnRH agonists and oral contraceptives) tend to be temporary but can be used preoperatively, in patients unsuitable for surgery, and postoperatively, while laparoscopic management with or without robotic assistance is feasible, and newer nerve-sparing surgery may reduce urinary complications after resection of deeply infiltrating disease. This paper is centrally about endometriosis — specifically urinary tract (ureteral and bladder) endometriosis and its management.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Urologic Diseases Urologic Diseases Combined Modality Therapy Cystoscopy Endometriosis Endometriosis Female Humans Urological Agents Urological Agents Urologic Diseases Urologic Diseases Urologic Surgical Procedures

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Cited by (50)

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