Diagnosis and management of endometriosis.

Anne L Mounsey, Anne Mounsey, Mounsey AL, Wilgus A, Alex Wilgus, David C. Slawson, Slawson DC
American family physician · 2006 · vol. 74(4) , pp. 594–600 · PMID:16939179 · W200447252
article OA: closed CC0 ⤵ 119 in-corpus citations
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Endometriosis diagnosis relies on surgical inspection and biopsy, with treatments ranging from symptomatic relief to hormonal therapy and definitive surgical intervention.

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Abstract

Signs and symptoms of endometriosis are nonspecific, and an acceptably accurate noninvasive diagnostic test has yet to be reported. Serum markers do not provide adequate diagnostic accuracy. The preferred method for diagnosis of endometriosis is surgical visual inspection of pelvic organs with histologic confirmation. Such diagnosis requires an experienced surgeon because the varied appearance of the disease allows less-obvious lesions to be overlooked. Empiric use of nonsteroidal anti-inflammatory drugs or acetaminophen is a reasonable symptomatic treatment, but the effectiveness of these agents has not been well-studied. Oral contraceptive pills, medroxyprogesterone acetate, and intrauterine levonorgestrel are relatively effective for pain relief. Danazol and various gonadotropin-releasing hormone analogues also are effective but may have significant side effects. There is limited evidence that surgical ablation of endometriotic deposits may decrease pain and increase fertility rates in women with endometriosis. Presacral neurectomy is particularly beneficial in women with midline pelvic pain. Hysterectomy and bilateral salpingo-oophorectomy definitively treat pain from endometriosis at 10 years in 90 percent of patients.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis CA-125 Antigen CA-125 Antigen CA-19-9 Antigen CA-19-9 Antigen Diagnosis, Differential Endometriosis Endometriosis Endometriosis Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Humans Prognosis Risk Factors

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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