Are there any clinical signs and symptoms that are related to endometriosis in infertile women?

R Matorras, Matorras R, Roberto Matorras, F Rodríguez, Rodríguez F, Fernándo Rodríguez, J I Pijoan, Pijoan JI, José Ignacio Pijoán, Soto E, Enrique Soto, E Soto, Pérez C, Carlos Enrique Tene Pérez, C Pérez, O Ramón, Olga Ramón, Ramón O, Rodríguez-Escudero F, Francisco J Rodrı́guez-Escudero, F Rodríguez-Escudero
American Journal of Obstetrics and Gynecology · 1996 · vol. 174(2) , pp. 620–623 · doi:10.1016/s0002-9378(96)70438-6 · PMID:8623795 · W2072014332
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⚙ AI-generated summary by claude@2026-07, 2026-07-16 ⓘ

This case-control study found that cul-de-sac nodularity and uterosacral tenderness with nodularity were the only clinical signs or symptoms of value in indicating endometriosis in infertile women.

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Abstract

ObjectiveOur purpose was to assess the physical signs and clinical symptoms associated with endometriosis in infertile women.Study designThis case-control study was carried out in an academic tertiary hospital. There were 174 infertile women with endometriosis and 174 infertile women without endometriosis, all of them studied by laparoscopy. Before laparoscopy a standard interview and a standard physical examination were performed.ResultsCul-de-sac nodularity was more frequent in infertile women with endometriosis than in infertile women without endometriosis (6.3% vs 0%). Although uterosacral tenderness was also more frequent in infertile women with endometriosis (7.5% vs 1.7%), uterosacral tenderness without nodularity was similar in both populations. Uterine retroversion and cul-de-sac obstruction frequencies were somewhat higher in the endometriosis group (p<0.10). The remaining signs and symptoms analyzed, including pelvic pain and dysmenorrhea, were similarly frequent in both populations. Symptoms were similarly frequent in all American Fertility Society stages, although adnexal mass was higher in stage IV.ConclusionUterosacral nodularity was pathognomonic of endometriosis in infertile women. Uterosacral nodularity and uterosacral tenderness (associated with uterosacral nodularity) were the only symptoms or signs of value to indicate endometriosis in infertile patients. The remaining clinical signs, as well as clinical symptoms, were of no value in diagnosing endometriosis in infertile women.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Infertility, Female Biopsy Case-Control Studies Endometriosis Endometriosis Endometriosis Female Humans Infertility, Female Laparoscopy Logistic Models Pelvic Pain Uterus Uterus

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References (12)

Cited by (50)

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