Shining light in a dark landscape: MRI evaluation of unusual localization of endometriosis

article OA: green CC0 ⤵ 30 in-corpus citations
AI-generated summary by claude@2026-06, 2026-06-08

This paper reviews magnetic resonance imaging findings for unusual pelvic and extrapelvic endometriosis locations, highlighting how the technique distinguishes endometriotic tissue from surrounding fibrosis.

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Abstract

Endometriosis is a disease distinguished by the presence of endometrial tissue outside the uterine cavity with intralesional recurrent bleeding and resulting fibrosis. The most common locations for endometriosis are the ovaries, pelvic peritoneum, uterosacral ligaments, and torus uterinus. Typical symptoms are secondary dysmenorrhea and cyclic or chronic pelvic pain. Unusual sites of endometriosis may be associated with specific symptoms depending on the localization. Atypical pelvic endometriosis localizations can occur in the cervix, vagina, round ligaments, ureter, and nerves. Moreover, rare extrapelvic endometriosis implants can be localized in the upper abdomen, subphrenic fold, or in the abdominal wall. Magnetic resonance imaging (MRI) represents a problem-solving tool among other imaging modalities. MRI is an advantageous technique, because of its multiplanarity, high contrast resolution, and lack of ionizing radiation. Our purpose is to remind the radiologists the possibility of atypical pelvic and extrapelvic endometriosis localizations and to illustrate the specific MRI findings. Endometriotic tissue with hemorrhagic content can be distinguished from adherences and fibrosis on MRI imaging. Radiologists should keep in mind these atypical localizations in patients with suspected endometriosis, in order to achieve the diagnosis and to help the clinicians in planning a correct and complete treatment strategy.

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Condition tags

mesh:D004715endometriosischronic_pelvic_paindysmenorrhea

MeSH descriptors

Endometriosis Magnetic Resonance Imaging Endometriosis Female Humans Magnetic Resonance Imaging Pelvis Pelvis

Citation neighborhood

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References (40)

Cited by (30)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:20:19.560968+00:00
License: CC0 · commercial use OK