Correlation Between Pain and Nerve Growth Factor Receptor Expression in Patients with Endometriosis Diagnosed by Transvaginal Color Ultrasound and Magnetic Resonance

Lin Mu, Mu L, Meng Wang, Wang M, Yue Yu
World neurosurgery · 2020 · vol. 138 , pp. 629–636 · doi:10.1016/j.wneu.2020.01.088 · PMID:31981787 · W3002048875
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study investigated the relationship between pain levels and nerve growth factor receptor expression in endometriosis patients diagnosed via ultrasound and MRI.

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Abstract

This paper explores the diagnosis of deep invasive endometriosis through retrospective data analysis, including deep infiltration and magnetic resonance imaging. The literature retrospectively collected data from 21 patients with deep invasive endometriosis who were admitted from 2012 to 2018. The patients were confirmed to have pain and nerve growth factor (NGF) receptor expression levels after operation and underwent vaginal color ultrasound and magnetic resonance imaging before surgery. The diagnostic results of color Doppler ultrasound and magnetic resonance imaging were retrospectively analyzed and compared with the surgical results, and the cumulative site and anatomic abnormalities of the diagnosis of deep invasive endometriosis were analyzed to determine the NGF receptor table. Through research it has been found that deep invasive endometriosis mainly involves the uterine fibula ligament, vagina, uterus rectum, rectum, ureter, and so forth. Patient pain is related to the expression level of NGF receptor, and its magnetic resonance mainly manifests as signals and structural obstacles, irregular thickening of the affected area, or nodular formation and deformation of adjacent tissues and organs. Through research and demonstration of deep invasive endometriosis, transvaginal color ultrasound and magnetic resonance imaging can not only accurately locate the expression levels of pain and NGF receptors, but also show the extent of the lesions, thereby studying pain and NGF receptor expression, which is an important method for preoperative examination and postoperative follow-up.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Magnetic Resonance Imaging Pain Receptor, Nerve Growth Factor Ultrasonography, Doppler, Color Vagina Adult Endometriosis Endometriosis Female Humans Magnetic Resonance Imaging Pain Pain Receptor, Nerve Growth Factor Retrospective Studies Ultrasonography, Doppler, Color Vagina

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