A histologic study of ovarian endometriosis with emphasis on hyperplastic and atypical changes.

B Czernobilsky, Bernard Czernobilsky, Czernobilsky B, Morris WJ, William Morris, W J Morris
Obstetrics and gynecology · 1979 · vol. 53(3) , pp. 318–23 · PMID:424103 · W30655731
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⚙ AI-generated summary by claude@2026-06, 2026-06-12 ⓘ

This histologic study of 194 ovarian endometriosis cases identified various epithelial types and findings, including reactive changes, adenomatous hyperplasia, and severe epithelial atypism in 3.6% of patients, suggesting possible neoplastic potential.

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Abstract

One hundred ninety-four cases of ovarian endometriosis, encountered during a 3-year period, were studied. In addition to endometrial-type epithelium and stroma that were present in each of these cases, oviduct-type epithelium was demonstrated in 26, papillary epithelial-lined projections in 7, and hobnail cells in 36 patients. Forty-three cases showed reactive epithelial changes, probably due to inflammation and regeneration. There were 4 cases of adenomatous hyperplasia. Severe epithelial atypism was seen in 7 patients (3.6%), 1 in conjunction with adenomatous hyperplasia. Although the areas of severe epithelial atypism in ovarian endometriosis may be of reactive origin, one must also consider the possibility that in some instances these atypical changes may constitute a neoplastic potential.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Ovarian Neoplasms Adult Aged Cell Nucleus Cell Nucleus Endometrial Hyperplasia Endometrial Hyperplasia Endometriosis Eosinophils Eosinophils Epithelium Epithelium Fallopian Tubes Fallopian Tubes Female Humans Hyperplasia Middle Aged Ovarian Neoplasms

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