Endometrioid adenocarcinoma of the ovary arising in atypical endometriosis.

Tadashi Terada
International journal of clinical and experimental pathology · 2012 · vol. 5(9) , pp. 924–7 · PMID:23119109 · W1527433584
article OA: green CC0 ⤵ 7 in-corpus citations
🔓 Open OA copy View on OpenAlex View on PubMed
⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This study reviewed 15 cases of ovarian endometrioid adenocarcinoma and found atypical endometriosis within the tumors in six cases, suggesting a potential transformation from atypical endometriosis to carcinoma.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Ovarian endometriosis can transform into malignant tumors, and ovarian carcinomas relatively frequently contain foci of endometriosis. In this study, the author reviewed 15 cases of endometrioid adenocarcinoma of the ovary in the last 15 years of our pathology laboratory in search for the presence of endometriosis within the tumor. Six (40%) of the 15 endometrioid adenocarcinoma were found to have endometriosis in the tumor. All of the endometriosis were atypical. The age of the 6 patients ranged from 44 year to 78 year with a median of 59 years. Grossly, the endometrial adenocarcinomas with endometriosis were characterized by unilocular cystic tumors in 5 cases and multilocular cystic tumor in one case. Histologically, the grade of endometrioid carcinoma was grade I in 3 cases, grade II in 2 cases and grade III in 1 case. Endometriosis was mixed with the tumors or was present adjacent to the tumor. The endometriosis was composed of a layer of atypical epithelium (atypical endometriosis), and gradual merges between endometriosis and carcinoma were present in 3 cases. These findings suggest that atypical endometriosis can transform into endometrioid carcinoma.

My notes (saved in your browser only)

Condition tags

mesh:D004715endometriosis

MeSH descriptors

Carcinoma, Endometrioid Cell Transformation, Neoplastic Endometriosis Neoplasms, Cystic, Mucinous, and Serous Ovarian Neoplasms Precancerous Conditions Adult Aged Carcinoma, Endometrioid Cell Transformation, Neoplastic Endometriosis Female Humans Middle Aged Neoplasm Grading Neoplasms, Cystic, Mucinous, and Serous Ovarian Neoplasms Precancerous Conditions

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (12)

Cited by (7)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:15:58.344756+00:00
License: CC0 · commercial use OK