Gene Expression in Endometriosis

Niraj Joshi; Ren‐Wei Su; Asgerally T. Fazleabas

doi:10.1007/978-3-030-28584-5_11

Gene Expression in Endometriosis

Niraj Joshi, Ren‐Wei Su, Asgerally T. Fazleabas

In: Endometrial Gene Expression · 2019 · pp. 159–180 · doi:10.1007/978-3-030-28584-5_11 · W2983568334

book-chapter OA: closed CC0 ⤵ 1 in-corpus citation

Limited metadata. Only one source feed has indexed this record so far — no abstract, full text, or open-access copy is available through Endo Lab. The publisher's page (linked below) is the canonical location for the actual content. If you have institutional access, use "Find at my library".

View at publisher → View on OpenAlex

⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

This study investigated how ectopic lesions alter eutopic endometrial gene expression in baboons, revealing that endometriosis impacts microRNA, Notch1, AKT, MAPK, ERK, and HIF1A-STAT3 signaling pathways, causing progesterone resistance and impaired decidualization.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

My notes (saved in your browser only)

Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

Cited by (1)

Establishment of an Immortalized Endometriotic Stromal Cell Line from Human Ovarian Endometrioma 2020

Source provenance

openalex: last seen: 2026-06-10T17:14:06.276822+00:00

License: CC0 · commercial use OK

[1] A baboon model for endometriosis: implications for fertility via openalex

[2] A Baboon Model for Inducing Endometriosis via openalex

[3] Aberrant activation of signal transducer and activator of transcription-3 (STAT3) signaling in endometriosis via openalex

[4] Aberrant Endometrial DNA Methylome and Associated Gene Expression in Women with Endometriosis via openalex

[5] Aberrant endometrial DNA methylome of homeobox A10 and catechol-O-methyltransferase in endometriosis via openalex

[6] Aberrant HOXA10 Methylation in Patients With Common Gynecologic Disorders: Implications for Reproductive Outcomes via openalex

[7] Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis via openalex

[8] Abnormal activation of Ras/Raf/MAPK and RhoA/ROCKII signalling pathways in eutopic endometrial stromal cells of patients with endometriosis via openalex

[9] Abnormally located SSEA1+/SOX9+ endometrial epithelial cells with a basalis-like phenotype in the eutopic functionalis layer may play a role in the pathogenesis of endometriosis via openalex

[10] Abundance and Localization of Progesterone Receptor Isoforms in Endometrium in Women With and Without Endometriosis and in Peritoneal and Ovarian Endometriotic Implants via openalex

[11] Activation of mutated K‐ras in donor endometrial epithelium and stroma promotes lesion growth in an intact immunocompetent murine model of endometriosis via openalex

[12] Akt as a possible intracellular mediator for decidualization in human endometrial stromal cells via openalex

[13] Altered expression of microRNA-451 in eutopic endometrium of baboons ( Papio anubis ) with endometriosis via openalex

[14] Altered expression of progesterone receptor isoforms A and B in human eutopic endometrium in endometriosis patients via openalex

[15] Altered Gene Expression Profiling in Endometrium: Evidence for Progesterone Resistance via openalex

[16] A Modified Baboon Model for Endometriosis via openalex

[17] Analysis of menstrual effluent: diagnostic potential for endometriosis via openalex

[18] Aromatase inhibitor treatment limits progression of peritoneal endometriosis in baboons via openalex

[19] cAMP-Response Element-Binding 3-Like Protein 1 (CREB3L1) is Required for Decidualization and its Expression is Decreased in Women with Endometriosis via openalex

[20] Changes in Eutopic Endometrial Gene Expression During the Progression of Experimental Endometriosis in the Baboon, Papio Anubis1 via openalex

[21] Clinical relevance of the baboon as a model for the study of endometriosis via openalex

[22] Coelomic Metaplasia Theory of Endometriosis: Evidence from in vivo Studies and an in vitro Experimental Model via openalex

[23] Contribution of Bone Marrow-Derived Stem Cells to Endometrium and Endometriosis via openalex

[24] Co-operation between the AKT and ERK signaling pathways may support growth of deep endometriosis in a fibrotic microenvironment in vitro† via openalex

[25] COUP-TFII Regulates Human Endometrial Stromal Genes Involved in Inflammation via openalex

[26] Decreased Notch Pathway Signaling in the Endometrium of Women With Endometriosis Impairs Decidualization via openalex

[27] Differential Expression of MicroRNAs between Eutopic and Ectopic Endometrium in Ovarian Endometriosis via openalex

[28] Differentially-Expressed miRNAs in Ectopic Stromal Cells Contribute to Endometriosis Development: The Plausible Role of miR-139-5p and miR-375 via openalex

[29] DNA methylation of HOXA10 in eutopic and ectopic endometrium via openalex

[30] Endometrial miR-543 Is Downregulated During the Implantation Window in Women With Endometriosis-Related Infertility via openalex

[31] Endometrial receptivity in the eutopic endometrium of women with endometriosis: it is affected, and let me show you why via openalex

[32] Endometrial stromal progesterone receptor-A/progesterone receptor-B ratio: no difference between women with and without endometriosis via openalex

[33] Endometriosis via openalex

[34] Endometriosis via openalex

[35] EPIDEMIOLOGY OF ENDOMETRIOSIS via openalex

[36] Epigenetic Disorder May Cause Downregulation of HOXA10 in the Eutopic Endometrium of Fertile Women With Endometriosis via openalex

[37] Epigenetic Dynamics of HOXA10 Gene in Infertile Women With Endometriosis via openalex

[38] Estrogen biosynthesis in endometriosis: molecular basis and clinical relevance via openalex

[39] Estrogen Receptor β Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis via openalex

[40] Etiology of infertility in monkeys with endometriosis: Measurement of peritoneal fluid prostaglandins via openalex

[41] Extracellular Signal-Regulated Kinase 1/2 Signaling Pathway Is Required for Endometrial Decidualization in Mice and Human via openalex

[42] FKBP4 is regulated by HOXA10 during decidualization and in endometriosis via openalex

[43] Functional MicroRNA Involved in Endometriosis via openalex

[44] Gene Expression Analysis of Endometrium Reveals Progesterone Resistance and Candidate Susceptibility Genes in Women with Endometriosis via openalex

[45] Genome-Wide DNA Methylation Analysis Predicts an Epigenetic Switch for GATA Factor Expression in Endometriosis via openalex

[46] Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis via openalex

[47] History of endometriosis may adversely affect the outcome in menopausal recipients of sibling oocytes via openalex

[48] Homeostasis Imbalance in the Endometrium of Women with Implantation Defects: The Role of Estrogen and Progesterone via openalex

[49] Hormonal Contraceptive Use and the Prevalence of Endometriotic Lesions at Different Regions within the Peritoneal Cavity via openalex

[50] Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis1 via openalex

[51] Human Endometriosis Tissue Microarray Reveals Site-specific Expression of Estrogen Receptors, Progesterone Receptor, and Ki67 via openalex

[52] Hypoxia-Induced MicroRNA-20a Expression Increases ERK Phosphorylation and Angiogenic Gene Expression in Endometriotic Stromal Cells via openalex

[53] Hypoxia‐inhibited dual‐specificity phosphatase‐2 expression in endometriotic cells regulates cyclooxygenase‐2 expression via openalex

[54] Incidence of Laparoscopically Confirmed Endometriosis by Demographic, Anthropometric, and Lifestyle Factors via openalex

[55] Increased Activation of the PI3K/AKT Pathway Compromises Decidualization of Stromal Cells from Endometriosis via openalex

[56] Increased Mitogen-Activated Protein Kinase Kinase/Extracellularly Regulated Kinase Activity in Human Endometrial Stromal Fibroblasts of Women with Endometriosis Reduces 3′,5′-Cyclic Adenosine 5′-Monophosphate Inhibition of Cyclin D1 via openalex

[57] Induction of endometriosis alters the peripheral and endometrial regulatory T cell population in the non-human primate via openalex

[58] Induction of endometriosis in the marmoset monkey (Callithrix jacchus) via openalex

[59] Inflammation influences steroid hormone receptors targeted by progestins in endometrial stromal cells from women with endometriosis via openalex

[60] Inflammatory Status Influences Aromatase and Steroid Receptor Expression in Endometriosis via openalex

[61] Integration analysis of microRNA and mRNA paired expression profiling identifies deregulated microRNA-transcription factor-gene regulatory networks in ovarian endometriosis via openalex

[62] Intrapelvic injection of menstrual endometrium causes endometriosis in baboons (Papio cynocephalus and Papio anubis) via openalex

[63] Invasion process of induced deep nodular endometriosis in an experimental baboon model: similarities with collective cell migration? via openalex

[64] Kinase signalling pathways in endometriosis: potential targets for non-hormonal therapeutics via openalex

[65] KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance via openalex

[66] Laparoscopic endometrioma resection increases peri-implantation endometrial HOXA-10 and HOXA-11 mRNA expression via openalex

[67] Laparoscopic surgery for subfertility associated with endometriosis via openalex

[68] Laparoscopic Surgery in Infertile Women with Minimal or Mild Endometriosis via openalex

[69] Lesion kinetics in a non-human primate model of endometriosis via openalex

[70] Mechanisms of endometrial progesterone resistance via openalex

[71] MicroRNA 135 Regulates HOXA10 Expression in Endometriosis via openalex

[72] MicroRNA expression profiling of eutopic secretory endometrium in women with versus without endometriosis via openalex

[73] MicroRNA-Regulated Pathways Associated with Endometriosis via openalex

[74] MicroRNAs and Endometriosis: Distinguishing Drivers from Passengers in Disease Pathogenesis via openalex

[75] miR-194-3p Represses the Progesterone Receptor and Decidualization in Eutopic Endometrium From Women With Endometriosis via openalex

[76] Molecular Biology of Endometriosis: From Aromatase to Genomic Abnormalities via openalex

[77] Molecular Evidence for Differences in Endometrium in Severe Versus Mild Endometriosis via openalex

[78] Nonhuman Primate Models for Translational Research in Endometriosis via openalex

[79] Notch-1 Signaling Activation and Progesterone Receptor Expression in Ectopic Lesions of Women With Endometriosis via openalex

[80] Outcome of patients with endometriosis in assisted reproduction: results from in-vitro fertilization and oocyte donation via openalex

[81] Ovarian steroid receptor expression in endometriosis and in two potential parent epithelia: endometrium and peritoneal mesothelium via openalex

[82] Overexpression of microRNA‐542‐3p attenuates the differentiating capacity of endometriotic stromal cells via openalex

[83] Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity via openalex

[84] Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities via openalex

[85] Pharmacological blockage of the CXCR4-CXCL12 axis in endometriosis leads to contrasting effects in proliferation, migration, and invasion† via openalex

[86] Possible Pathophysiological Roles of Mitogen‐Activated Protein Kinases (MAPKs) in Endometriosis via openalex

[87] Presurgical management of dysmenorrhea and endometriosis in a patient with Mayer-Rokitansky-Kuster-Hauser syndrome via openalex

[88] Progesterone Resistance in Endometriosis: an Acquired Property? via openalex

[89] Progesterone resistance in endometriosis is modulated by the altered expression of microRNA-29c and FKBP4 via openalex

[90] Promoter Hypermethylation of Progesterone Receptor Isoform B (PR-B) in Endometriosis via openalex

[91] Promoter Methylation Regulates Estrogen Receptor 2 in Human Endometrium and Endometriosis1 via openalex

[92] Protein Inhibitor of Activated STAT3 (PIAS3) Is Down-Regulated in Eutopic Endometrium of Women with Endometriosis via openalex

[93] Protein kinase inhibitors can control the progression of endometriosis <i>in vitro</i> and <i>in vivo</i> via openalex

[94] Reduced expression of HOXA10 in the midluteal endometrium from infertile women with minimal endometriosis via openalex

[95] Role of Estrogen Receptor-β in Endometriosis via openalex

[96] Role of microRNAs in Gynecological Pathology via openalex

[97] Steroidogenic Enzyme and Key Decidualization Marker Dysregulation in Endometrial Stromal Cells from Women with Versus Without Endometriosis1 via openalex

[98] Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity via openalex

[99] Surgery for bladder endometriosis: long-term results and concomitant management of associated posterior deep lesions via openalex

[100] [The action of p38 MAP kinase and its inhibitors on endometriosis]. via openalex