Altered expression of microRNA-451 in eutopic endometrium of baboons ( Papio anubis ) with endometriosis
This study investigated microRNA expression in baboon eutopic endometrium and found altered expression of microRNA-451 in animals with induced endometriosis.
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The study examined expression of microRNA-451 in eutopic endometrium from baboons with experimentally characterized endometriosis, using tissue sampling and expression measurement to compare levels between affected and control groups. The main finding was altered microRNA-451 expression in the eutopic endometrium associated with endometriosis. The paper’s caveat is that conclusions rely on this specific non-human primate model and on the measured microRNA expression in eutopic tissue rather than broader mechanistic validation. This paper is centrally about endometriosis — specifically, it reports altered microRNA-451 expression in eutopic endometrium of baboons with endometriosis.
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Cited by (23)
- Identification and exploration of potential N6-methylation related mRNAs in endometriosis 2024
- The Known, the Unknown and the Future of the Pathophysiology of Endometriosis 2024
- MicroRNA-210-3p Regulates Endometriotic Lesion Development by Targeting IGFBP3 in Baboons and Women with Endometriosis 2023
- Dissecting the miR-451a-Mif Pathway in Endometriosis Pathophysiology Using a Syngeneic Mouse Model: Temporal Expression of Lesion Mif Receptors, Cd74 and Cxcr4 2022
- Roles of microRNAs in Regulating Apoptosis in the Pathogenesis of Endometriosis 2022
- METTL3 and METTL14-mediated N6-methyladenosine modification promotes cell proliferation and invasion in a model of endometriosis 2022
- AP-1 Subunit JUNB Promotes Invasive Phenotypes in Endometriosis 2022
- Clinical consequences of defective decidualization 2021
- Genetic and epigenetic changes in the eutopic endometrium of women with endometriosis: association with decreased endometrial αvβ3 integrin expression 2021
- Establishment of endometriotic models: the past and future 2020
- miR-45la Inhibition Reduces Established Endometriosis Lesions in Mice 2019
- MicroRNAs in endometriosis: biological function and emerging biomarker candidates† 2019
- MicroRNA-451 is downregulated in the follicular fluid of women with endometriosis and influences mouse and human embryonic potential 2019
- Gene Expression in Endometriosis 2019
- Human endometriotic lesion expression of the miR-144-3p/miR-451a cluster, its correlation with markers of cell survival and origin of lesion content 2019
- Endometrium metabolomic profiling reveals potential biomarkers for diagnosis of endometriosis at minimal-mild stages 2018
- Hypoxia-induced autophagy, epithelial to mesenchymal transition, and invasion in the pathophysiology of endometriosis: a perspective 2018
- miR-194-3p Represses the Progesterone Receptor and Decidualization in Eutopic Endometrium From Women With Endometriosis 2018
- Challenges in endometriosis miRNA studies — From tissue heterogeneity to disease specific miRNAs 2017
- Efeito da remoção cirúrgica das lesões de endometriose profunda na expressão dos microRNAs-21, -451 e -29c e da proteína FKBP52 2017
- Progesterone resistance in endometriosis is modulated by the altered expression of microRNA-29c and FKBP4 2016
- Serum miR-451a Levels Are Significantly Elevated in Women With Endometriosis and Recapitulated in Baboons (Papio anubis) With Experimentally-Induced Disease 2016
- Optimal uterine anatomy and physiology necessary for normal implantation and placentation 2016
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