Niraj Joshi

ORCID: 0000-0002-2334-6819 · 18 papers in corpus · active 2011-2025

Study types

  • article 12
  • other 3
  • book-chapter 1
  • erratum 1
  • preprint 1

Condition tags

  • endometriosis 18
  • infertility 4
  • chronic_pelvic_pain 3
  • die_deep_infiltrating 3
  • endometrioma 1
other 2025
Reproduction (Cambridge, England) ·doi:10.1530/REP-24-0355

IN BRIEF: The HIPPO signaling effectors YAP1 and WWTR1 are required for murine pregnancy initiation, and mutation of these factors compromises the decidualization response and overall pregnancy success. ABSTRACT: Endometrial stromal cell d…

erratum 2024
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-024-01466-2
other 2024
International journal of molecular sciences ·doi:10.3390/ijms25168994

Endometriosis is one of the most common causes of chronic pelvic pain and infertility that affects 10% of women of reproductive age. It is currently defined as the presence of endometrial epithelial and stromal cells at ectopic sites; howev…

other 2024
bioRxiv : the preprint server for biology ·doi:10.1101/2024.05.09.592984

Endometrial stromal cell decidualization is required for pregnancy success. Although this process is integral to fertility, many of the intricate molecular mechanisms contributing to decidualization remain undefined. One pathway that has be…

article 2023
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-023-01253-5

MicroRNAs (miRs) play an important role in the pathophysiology of endometriosis; however, the role of miR-210 in endometriosis remains unclear. This study explores the role of miR-210 and its targets, IGFBP3 and COL8A1, in ectopic lesion gr…

article 2023
JCI insight ·doi:10.1172/jci.insight.160815

The development and progression of endometriotic lesions are poorly understood, but immune cell dysfunction and inflammation are closely associated with the pathophysiology of endometriosis. There is a need for 3D in vitro models to permit …

article 2022
Reproduction (Cambridge, England) ·doi:10.1530/rep-22-0123

Although a non-malignant gynecological disorder, endometriosis displays some pathogenic features of malignancy, such as cell proliferation, migration, invasion and adaptation to hypoxia. Current treatments of endometriosis include pharmacot…

preprint 2022
·doi:10.1101/2022.02.15.480583

ABSTRACT The development and progression of endometriotic lesions are poorly understood, but immune cell dysfunction and inflammation are closely associated with the pathophysiology of endometriosis. A lack of suitable 3D in vitro models pe…

article 2021
Molecular human reproduction ·doi:10.1093/molehr/gaab018

About 40% of women with infertility and 70% of women with pelvic pain suffer from endometriosis. The pregnancy rate in women undergoing IVF with low endometrial integrin αvβ3 (LEI) expression is significantly lower compared to the women wit…

article 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00228-0
article 2020
·doi:10.17615/h6k0-pt92

Context: Endometriosis results in aberrant gene expression in the eutopic endometrium (EuE) and subsequent progesterone resistance. MicroRNA (miR) microarray data in a baboon model of endometriosis showed an increased expression of miR-29c.…

book-chapter 2019
·doi:10.1007/978-3-030-28584-5_11
article 2016
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2016-2076

Context: Endometriosis results in aberrant gene expression in the eutopic endometrium (EuE) and subsequent progesterone resistance. MicroRNA (miR) microarray data in a baboon model of endometriosis showed an increased expression of miR-29c.…

article 2016
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719116681519
article 2014
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2014-3720

CONTEXT: Endometriosis is a common gynecological disease affecting one in 10 women of reproductive age and is a major cause of pelvic pain and impaired fertility. Endometrial stromal cells of women with endometriosis exhibit a reduced respo…

article 2014
·doi:10.1016/j.fertnstert.2014.07.173
article 2012
·doi:10.1093/biolreprod/87.s1.323

Endometriosis is a gynecological disorder characterized by severe chronic pelvic pain and infertility. Although the causes of endometriosis associated infertility are not well defined it is evident that the presence of the disease results i…

article 2011
·doi:10.1093/biolreprod/85.s1.395

Endometriosis is one of the most common gynecological disorders which are a cause of chronic pelvic pain and infertility. The molecular mechanisms associated with the pathophysiology of the endometriosis related infertility are poorly under…