Endometrial receptivity in the eutopic endometrium of women with endometriosis: it is affected, and let me show you why

Bruce A Lessey; J Julie Kim; Julie Kim

doi:10.1016/j.fertnstert.2017.05.031

Endometrial receptivity in the eutopic endometrium of women with endometriosis: it is affected, and let me show you why

Bruce A Lessey, J Julie Kim, Julie Kim

Fertility and sterility · 2017 · vol. 108(1) , pp. 19–27 · doi:10.1016/j.fertnstert.2017.05.031 · PMID:28602477 · W2624413373

review OA: bronze CC0 ⤵ 178 in-corpus citations

🔓 Open OA copy View on OpenAlex View on PubMed View at publisher

⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study investigated and demonstrated alterations in endometrial receptivity within the eutopic endometrium of women diagnosed with endometriosis.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

My notes (saved in your browser only)

Condition tags

mesh:D004715endometriosis

MeSH descriptors

Embryo Implantation Embryo Transfer Endometriosis Endometrium Fertilization in Vitro Infertility, Female Infertility, Female Animals Embryo Implantation Embryo Transfer Endometriosis Endometrium Endometrium Evidence-Based Medicine Female Fertilization in Vitro Humans Infertility, Female Menstrual Cycle Menstrual Cycle

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

Aberrant activation of signal transducer and activator of transcription-3 (STAT3) signaling in endometriosis via openalex
Aberrant integrin expression in the endometrium of women with endometriosis via openalex
Aberrant integrin expression in the endometrium of women with endometriosis. via openalex
Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis via openalex
Akt as a possible intracellular mediator for decidualization in human endometrial stromal cells via openalex
Altered Gene Expression Profiling in Endometrium: Evidence for Progesterone Resistance via openalex
Anomalies in the inflammatory response in endometriosis and possible consequences: a review. via openalex
A prospective cohort study of endometriosis and subsequent risk of infertility via openalex
Aromatase inhibitors: the next generation of therapeutics for endometriosis? via openalex
Artificial insemination by husband in unexplained infertility compared with infertility associated with peritoneal endometriosis via openalex
Benefit of Diagnostic Laparoscopy for Patients with Unexplained Infertility and Normal Hysterosalpingography Findings via openalex
Biomarkers of endometriosis via openalex
cAMP-Response Element-Binding 3-Like Protein 1 (CREB3L1) is Required for Decidualization and its Expression is Decreased in Women with Endometriosis via openalex
COUP-TFII Regulates Human Endometrial Stromal Genes Involved in Inflammation via openalex
CXCL8 enhances proliferation and growth and reduces apoptosis in endometrial stromal cells in an autocrine manner via a CXCR1-triggered PTEN/AKT signal pathway via openalex
Cytokine profiles in serum and peritoneal fluid from infertile women with and without endometriosis via openalex
Dating the Endometrial Biopsy via openalex
Decreased Notch Pathway Signaling in the Endometrium of Women With Endometriosis Impairs Decidualization via openalex
Differential expression of genes in eutopic and ectopic endometrium from patients with ovarian endometriosis via openalex
Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis via openalex
DNA microarray analysis of gene expression in eutopic endometrium from patients with deep endometriosis using laser capture microdissection via openalex
Effect of endometriosis on in vitro fertilization via openalex
Effect of peritoneal fluid from women with endometriosis on implantation in the mouse model via openalex
Endometriosis and infertility: a committee opinion via openalex
Endometriosis and infertility: a laparoscopic study of endometriosis among fertile and infertile women via openalex
Endometriosis and spontaneous abortion via openalex
Endometriosis: disease pathophysiology and the role of prostaglandins via openalex
Endometriosis: pathogenesis and treatment via openalex
Endometriosis: the pathophysiology as an estrogen-dependent disease via openalex
Endometrium from women with endometriosis shows increased proliferation activity via openalex
Estrogen receptor-alpha (ER-alpha) and defects in uterine receptivity in women via openalex
Eutopic Endometrium in Women with Endometriosis: Ground Zero for the Study of Implantation Defects via openalex
Evaluation of Endometrial Inflammation by Quantification of Macrophages, T Lymphocytes, and Interleukin-1 and -6 in Human Endometrium via openalex
Experimental endometriosis in laboratory animals as a research model. via openalex
Experimental evidence for failure to implant as a mechanism of infertility associated with endometriosis via openalex
Expression of Aromatase Cytochrome P450 Protein and Messenger Ribonucleic Acid in Human Endometriotic and Adenomyotic Tissues but not in Normal Endometrium1 via openalex
Expression of interleukin-8 and monocyte chemotactic protein-1 in adenomyosis via openalex
Expression Profiling of Endometrium from Women with Endometriosis Reveals Candidate Genes for Disease-Based Implantation Failure and Infertility via openalex
Extracellular Signal-Regulated Kinase 1/2 Signaling Pathway Is Required for Endometrial Decidualization in Mice and Human via openalex
Gene Expression Analysis of Endometrium Reveals Progesterone Resistance and Candidate Susceptibility Genes in Women with Endometriosis via openalex
Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis via openalex
High endometrial aromatase P450 mRNA expression is associated with poor IVF outcome via openalex
High prevalence of endometriosis in infertile women with normal ovulation and normospermic partners via openalex
History of endometriosis may adversely affect the outcome in menopausal recipients of sibling oocytes via openalex
Homeostasis Imbalance in the Endometrium of Women with Implantation Defects: The Role of Estrogen and Progesterone via openalex
IL-17A Contributes to the Pathogenesis of Endometriosis by Triggering Proinflammatory Cytokines and Angiogenic Growth Factors via openalex
IL6 and acute phase plasma proteins in peritoneal fluid of women with endometriosis via openalex
Immune-inflammation gene signatures in endometriosis patients via openalex
Implantation Defects in Infertile Women with Endometriosis via openalex
Implications of immune dysfunction on endometriosis associated infertility via openalex
Incidence, symptoms, and signs of endometriosis in fertile and infertile women. via openalex
Increased Activation of the PI3K/AKT Pathway Compromises Decidualization of Stromal Cells from Endometriosis via openalex
Increased Mitogen-Activated Protein Kinase Kinase/Extracellularly Regulated Kinase Activity in Human Endometrial Stromal Fibroblasts of Women with Endometriosis Reduces 3′,5′-Cyclic Adenosine 5′-Monophosphate Inhibition of Cyclin D1 via openalex
Induction of endometriosis alters the peripheral and endometrial regulatory T cell population in the non-human primate via openalex
Inflammation in Reproductive Disorders via openalex
Inflammatory Status Influences Aromatase and Steroid Receptor Expression in Endometriosis via openalex
Influence of Endometriosis on Assisted Reproductive Technology Outcomes via openalex
Interleukin-17F increases the secretion of interleukin-8 and the expression of cyclooxygenase 2 in endometriosis via openalex
In vitro fertilization is a successful treatment in endometriosis-associated infertility via openalex
Is Endometriosis Associated with Systemic Subclinical Inflammation? via openalex
Laparoscopic endometrioma resection increases peri-implantation endometrial HOXA-10 and HOXA-11 mRNA expression via openalex
Laparoscopic surgery for subfertility associated with endometriosis via openalex
Laparoscopic surgery for subfertility associated with endometriosis via openalex
Laparoscopic Surgery in Infertile Women with Minimal or Mild Endometriosis via openalex
Laparoscopy should be strongly considered for women with unexplained infertility via openalex
Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis via openalex
L-Selectin ligands in human endometrium: comparison of fertile and infertile subjects via openalex
Medical management of endometriosis: emerging evidence linking inflammation to disease pathophysiology. via openalex
MicroRNA-Regulated Pathways Associated with Endometriosis via openalex
Nuclear factor κB pathway and interleukin-6 are affected in eutopic endometrium of women with endometriosis via openalex
Outcome of patients with endometriosis in assisted reproduction: results from in-vitro fertilization and oocyte donation via openalex
Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis via openalex
Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis1 via openalex
Progesterone resistance in endometriosis: origins, consequences and interventions via openalex
Prostaglandin E <sub>2</sub> : the master of endometriosis? via openalex
Protein Inhibitor of Activated STAT3 (PIAS3) Is Down-Regulated in Eutopic Endometrium of Women with Endometriosis via openalex
Reduced progesterone action during endometrial maturation: A potential risk factor for the development of endometriosis via openalex
Role of laparoscopic treatment of endometriosis in patients with failed in vitro fertilization cycles via openalex
Steroidogenic Enzyme and Key Decidualization Marker Dysregulation in Endometrial Stromal Cells from Women with Versus Without Endometriosis1 via openalex
Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity via openalex
Surgical Induction of Endometriosis in the Rabbit: Effects on Fertility and Concentrations of Peritoneal Fluid Prostaglandins via openalex
The effectiveness of ovulation induction and intrauterine insemination in the treatment of persistent infertility: a meta-analysis via openalex
Transcriptional Characterizations of Differences between Eutopic and Ectopic Endometrium via openalex
W4240600715 via openalex
W4243015558 via openalex
W4243180786 via openalex
W4245738220 via openalex
W4292365867 via openalex
W4295689030 via openalex
W6603827244 via openalex
W6605969444 via openalex
W6631052780 via openalex
W6638756373 via openalex
W6640900880 via openalex
W6645299560 via openalex
W6658221620 via openalex
W6666665120 via openalex
W6675112554 via openalex
W6822317149 via openalex
W6827039142 via openalex

Cited by (50)

Source provenance

europepmc: last seen: 2026-06-04T01:30:01.192114+00:00
openalex: last seen: 2026-06-10T17:14:06.276822+00:00
pubmed: last seen: 2026-05-13T22:20:25.745717+00:00

License: CC0 · commercial use OK

[1] Aberrant activation of signal transducer and activator of transcription-3 (STAT3) signaling in endometriosis via openalex

[2] Aberrant integrin expression in the endometrium of women with endometriosis via openalex

[3] Aberrant integrin expression in the endometrium of women with endometriosis. via openalex

[4] Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis via openalex

[5] Akt as a possible intracellular mediator for decidualization in human endometrial stromal cells via openalex

[6] Altered Gene Expression Profiling in Endometrium: Evidence for Progesterone Resistance via openalex

[7] Anomalies in the inflammatory response in endometriosis and possible consequences: a review. via openalex

[8] A prospective cohort study of endometriosis and subsequent risk of infertility via openalex

[9] Aromatase inhibitors: the next generation of therapeutics for endometriosis? via openalex

[10] Artificial insemination by husband in unexplained infertility compared with infertility associated with peritoneal endometriosis via openalex

[11] Benefit of Diagnostic Laparoscopy for Patients with Unexplained Infertility and Normal Hysterosalpingography Findings via openalex

[12] Biomarkers of endometriosis via openalex

[13] cAMP-Response Element-Binding 3-Like Protein 1 (CREB3L1) is Required for Decidualization and its Expression is Decreased in Women with Endometriosis via openalex

[14] COUP-TFII Regulates Human Endometrial Stromal Genes Involved in Inflammation via openalex

[15] CXCL8 enhances proliferation and growth and reduces apoptosis in endometrial stromal cells in an autocrine manner via a CXCR1-triggered PTEN/AKT signal pathway via openalex

[16] Cytokine profiles in serum and peritoneal fluid from infertile women with and without endometriosis via openalex

[17] Dating the Endometrial Biopsy via openalex

[18] Decreased Notch Pathway Signaling in the Endometrium of Women With Endometriosis Impairs Decidualization via openalex

[19] Differential expression of genes in eutopic and ectopic endometrium from patients with ovarian endometriosis via openalex

[20] Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis via openalex

[21] DNA microarray analysis of gene expression in eutopic endometrium from patients with deep endometriosis using laser capture microdissection via openalex

[22] Effect of endometriosis on in vitro fertilization via openalex

[23] Effect of peritoneal fluid from women with endometriosis on implantation in the mouse model via openalex

[24] Endometriosis and infertility: a committee opinion via openalex

[25] Endometriosis and infertility: a laparoscopic study of endometriosis among fertile and infertile women via openalex

[26] Endometriosis and spontaneous abortion via openalex

[27] Endometriosis: disease pathophysiology and the role of prostaglandins via openalex

[28] Endometriosis: pathogenesis and treatment via openalex

[29] Endometriosis: the pathophysiology as an estrogen-dependent disease via openalex

[30] Endometrium from women with endometriosis shows increased proliferation activity via openalex

[31] Estrogen receptor-alpha (ER-alpha) and defects in uterine receptivity in women via openalex

[32] Eutopic Endometrium in Women with Endometriosis: Ground Zero for the Study of Implantation Defects via openalex

[33] Evaluation of Endometrial Inflammation by Quantification of Macrophages, T Lymphocytes, and Interleukin-1 and -6 in Human Endometrium via openalex

[34] Experimental endometriosis in laboratory animals as a research model. via openalex

[35] Experimental evidence for failure to implant as a mechanism of infertility associated with endometriosis via openalex

[36] Expression of Aromatase Cytochrome P450 Protein and Messenger Ribonucleic Acid in Human Endometriotic and Adenomyotic Tissues but not in Normal Endometrium1 via openalex

[37] Expression of interleukin-8 and monocyte chemotactic protein-1 in adenomyosis via openalex

[38] Expression Profiling of Endometrium from Women with Endometriosis Reveals Candidate Genes for Disease-Based Implantation Failure and Infertility via openalex

[39] Extracellular Signal-Regulated Kinase 1/2 Signaling Pathway Is Required for Endometrial Decidualization in Mice and Human via openalex

[40] Gene Expression Analysis of Endometrium Reveals Progesterone Resistance and Candidate Susceptibility Genes in Women with Endometriosis via openalex

[41] Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis via openalex

[42] High endometrial aromatase P450 mRNA expression is associated with poor IVF outcome via openalex

[43] High prevalence of endometriosis in infertile women with normal ovulation and normospermic partners via openalex

[44] History of endometriosis may adversely affect the outcome in menopausal recipients of sibling oocytes via openalex

[45] Homeostasis Imbalance in the Endometrium of Women with Implantation Defects: The Role of Estrogen and Progesterone via openalex

[46] IL-17A Contributes to the Pathogenesis of Endometriosis by Triggering Proinflammatory Cytokines and Angiogenic Growth Factors via openalex

[47] IL6 and acute phase plasma proteins in peritoneal fluid of women with endometriosis via openalex

[48] Immune-inflammation gene signatures in endometriosis patients via openalex

[49] Implantation Defects in Infertile Women with Endometriosis via openalex

[50] Implications of immune dysfunction on endometriosis associated infertility via openalex

[51] Incidence, symptoms, and signs of endometriosis in fertile and infertile women. via openalex

[52] Increased Activation of the PI3K/AKT Pathway Compromises Decidualization of Stromal Cells from Endometriosis via openalex

[53] Increased Mitogen-Activated Protein Kinase Kinase/Extracellularly Regulated Kinase Activity in Human Endometrial Stromal Fibroblasts of Women with Endometriosis Reduces 3′,5′-Cyclic Adenosine 5′-Monophosphate Inhibition of Cyclin D1 via openalex

[54] Induction of endometriosis alters the peripheral and endometrial regulatory T cell population in the non-human primate via openalex

[55] Inflammation in Reproductive Disorders via openalex

[56] Inflammatory Status Influences Aromatase and Steroid Receptor Expression in Endometriosis via openalex

[57] Influence of Endometriosis on Assisted Reproductive Technology Outcomes via openalex

[58] Interleukin-17F increases the secretion of interleukin-8 and the expression of cyclooxygenase 2 in endometriosis via openalex

[59] In vitro fertilization is a successful treatment in endometriosis-associated infertility via openalex

[60] Is Endometriosis Associated with Systemic Subclinical Inflammation? via openalex

[61] Laparoscopic endometrioma resection increases peri-implantation endometrial HOXA-10 and HOXA-11 mRNA expression via openalex

[62] Laparoscopic surgery for subfertility associated with endometriosis via openalex

[63] Laparoscopic surgery for subfertility associated with endometriosis via openalex

[64] Laparoscopic Surgery in Infertile Women with Minimal or Mild Endometriosis via openalex

[65] Laparoscopy should be strongly considered for women with unexplained infertility via openalex

[66] Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis via openalex

[67] L-Selectin ligands in human endometrium: comparison of fertile and infertile subjects via openalex

[68] Medical management of endometriosis: emerging evidence linking inflammation to disease pathophysiology. via openalex

[69] MicroRNA-Regulated Pathways Associated with Endometriosis via openalex

[70] Nuclear factor κB pathway and interleukin-6 are affected in eutopic endometrium of women with endometriosis via openalex

[71] Outcome of patients with endometriosis in assisted reproduction: results from in-vitro fertilization and oocyte donation via openalex

[72] Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis via openalex

[73] Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis1 via openalex

[74] Progesterone resistance in endometriosis: origins, consequences and interventions via openalex

[75] Prostaglandin E <sub>2</sub> : the master of endometriosis? via openalex

[76] Protein Inhibitor of Activated STAT3 (PIAS3) Is Down-Regulated in Eutopic Endometrium of Women with Endometriosis via openalex

[77] Reduced progesterone action during endometrial maturation: A potential risk factor for the development of endometriosis via openalex

[78] Role of laparoscopic treatment of endometriosis in patients with failed in vitro fertilization cycles via openalex

[79] Steroidogenic Enzyme and Key Decidualization Marker Dysregulation in Endometrial Stromal Cells from Women with Versus Without Endometriosis1 via openalex

[80] Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity via openalex

[81] Surgical Induction of Endometriosis in the Rabbit: Effects on Fertility and Concentrations of Peritoneal Fluid Prostaglandins via openalex

[82] The effectiveness of ovulation induction and intrauterine insemination in the treatment of persistent infertility: a meta-analysis via openalex

[83] Transcriptional Characterizations of Differences between Eutopic and Ectopic Endometrium via openalex

[84] W4240600715 via openalex

[85] W4243015558 via openalex

[86] W4243180786 via openalex

[87] W4245738220 via openalex

[88] W4292365867 via openalex

[89] W4295689030 via openalex

[90] W6603827244 via openalex

[91] W6605969444 via openalex

[92] W6631052780 via openalex

[93] W6638756373 via openalex

[94] W6640900880 via openalex

[95] W6645299560 via openalex

[96] W6658221620 via openalex

[97] W6666665120 via openalex

[98] W6675112554 via openalex

[99] W6822317149 via openalex

[100] W6827039142 via openalex