Biomarkers of endometriosis

E.-E.R. Othman, Essam El-Din R Othman, Daniela Hornung, Ayman Al-Hendy, Ayman Al‐Hendy
Expert opinion on medical diagnostics · 2008 · vol. 2(7) , pp. 741–752 · doi:10.1517/17530059.2.7.741 · PMID:23495814 · W2122367488
article OA: closed CC0 ⤵ 19 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This review analyzed studies on blood and endometrial biomarkers, finding some with good specificity but none with high sensitivity for non-surgical endometriosis diagnosis.

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Abstract

BACKGROUND: Diagnosis of endometriosis is surgical through laparoscopy, which is invasive, costly and associated with potential complications. OBJECTIVES: A non-invasive test for diagnosis of endometriosis will focus the use of laparoscopy on women who are highly suspected of having endometriosis. This review includes studies about different biomarkers for endometriosis and their potential for the non-surgical diagnosis of this disease. METHODS: This review covers studies that investigated different biomarkers in blood or endometrium. Studies that identified definite cutoff points and evaluated the diagnostic performance of the biomarker as a blood test for endometriosis are focused on. RESULTS/CONCLUSIONS: Some of the markers investigated showed a good specificity, none of them showed a high sensitivity. More multi-center studies involving larger numbers of patients are required to identify the most useful biomarker.

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Condition tags

endometriosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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