Biomarkers for Endometriosis in Saliva, Urine, and Peritoneal Fluid

Ndeye-Aicha Gueye, Jamie Stanhiser, Lindsey N. Valentine, Alexander Kotlyar, Linnea R. Goodman, Tommaso Falcone
In: Biomarkers for Endometriosis · 2017 · pp. 141–163 · doi:10.1007/978-3-319-59856-7_8 · W2759864180
book-chapter OA: closed CC0 ⤵ 6 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This chapter reviews noninvasive urinary and salivary, and semi-invasive peritoneal biomarkers for screening and diagnosing endometriosis in symptomatic women with normal ultrasound findings.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This chapter reviews noninvasive and semi-invasive approaches for finding biologic biomarkers for endometriosis, focusing on women with chronic pelvic pain and/or infertility who have normal transvaginal ultrasound, and considers urinary, salivary, and peritoneal samples alongside some genetic and hormonal marker studies. It reports that while many candidate urinary peptides/proteins and peritoneal markers such as cytokines, immune modulators, and growth factors have been studied, no single biomarker is clearly superior, and biomarker panels combining multiple markers are likely needed. The chapter explicitly notes that findings require validation in larger, more diverse sample sizes and that applicability into clinical practice is not yet established. Relevance to endometriosis: the paper’s entire scope is endometriosis biomarkers in saliva, urine, and peritoneal fluid, aiming to address diagnostic delays despite normal ultrasound.

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endometriosis

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last seen: 2026-06-10T17:14:06.276822+00:00
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