Endometriosis: Associations with Menorrhagia, Infertility and Oral Contraceptives
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This retrospective study of 163 women found that 76% had menorrhagia, 10% complained of infertility, and 13% had used oral contraceptives, suggesting a possible role for estrogen sensitivity in endometriosis pathogenesis.
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Abstract
In a retrospective study of 163 women with endometriosis, 76% had a history of menorrhagia, a larger percentage than that which might be normally expected. Only 10% of the women complained of infertility, while 13% had used oral contraceptives regularly, a much smaller proportion than expected. These findings are discussed in terms of the pathogenesis of endometriosis and the possible prophylactic role of oral contraceptives. The authors suggest the possibility that increased sensitivity to estrogens may lead to the development of endometriosis in some women.
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- Metformin Alleviates Endometriosis and Potentiates Endometrial Receptivity via Decreasing VEGF and MMP9 and Increasing Leukemia Inhibitor Factor and HOXA10 2022
- Plasma and Peritoneal Poly (ADP-Ribose) Polymerase Levels in Patients with Endometriosis 2022
- Autoimmunity and infertility 2022
- Endometriosis: A Retrospective Analysis on Diagnostic Data in a Cohort of 4,401 Patients 2021
- Age at Menarche, Duration of Monthly Flow and Cycle Length as Risk Factors for Endometriosis in Sub-Sahara Black African Women 2021
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- The role of robotic surgery for endometriosis 2020
- Infertility Associated to Endometriosis: Clarifying Some Important Controversies 2019
- Single-cell RNA sequencing of oocytes from ovarian endometriosis patients reveals a differential transcriptomic profile associated with lower quality 2019
- Evaluation of miR‑135a/b expression in endometriosis lesions 2019
- Ovarian Endometrioid and Clear-Cell Tumors 2019
- The link between immunity, autoimmunity and endometriosis: a literature update 2018
- [Effect of GnRHa therapy following conservative laparoscopic surgery for endometriosis on clinical pregnant rate in patients with endometriosis-associated infertility]. 2018
- Evaluation of PAI-1 in endometriosis using a homologous immunocompetent mouse model† 2018
- Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a multicenter, randomized, controlled trial 2017
- Biomarkers for Endometriosis in Saliva, Urine, and Peritoneal Fluid 2017
- Identifying biomarkers for non-invasive diagnosis of endometriosis 2016
- Implications of immune dysfunction on endometriosis associated infertility 2016
- Preoperative assessment and diagnosis of endometriosis 2015
- Diminuição da expressão do miRNA 135 na fase secretora do ciclo menstrual em pacientes com endometriose 2014
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- Pelvic and Extragenital Endometriosis: A Review of the Surgical Management of Deeply Infiltrating Lesions 2013
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- Endometriosis and Oxidative Stress 2012
- Combined mRNA microarray and proteomic analysis of eutopic endometrium of women with and without endometriosis 2012
- Acquired haemophilia in severe pelvic endometriosis: a new association? 2011
- Innovations in conservative endometriosis treatment: an updated review. 2011
- Interleukin-1β induces cyclooxygenase-2 expression and promotes the invasive ability of human mesenchymal stem cells derived from ovarian endometrioma 2011
- Effects of simvastatin on the proliferation and apoptosis of human endometrial stromal cells from women with endometriosis 2010
- Oral contraceptives and risk of endometriosis: a systematic review and meta-analysis 2010
- Abnormal regulation of chemokine TECK and its receptor CCR9 in the endometriotic milieu is involved in pathogenesis of endometriosis by way of enhancing invasiveness of endometrial stromal cells 2010
- Comparative study of human eutopic and ectopic endometrial mesenchymal stem cells and the development of an in vivo endometriotic invasion model 2010
- Medical treatment of endometriosis. 2009
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- The role of the oxidative-stress in the endometriosis-related infertility 2009
- Eutopic endometrial interleukin-18 system mRNA and protein expression at the level of endometrial-myometrial interface in adenomyosis patients 2009
- Impact of endometriosis on quality of life: A pilot study 2009
- Endometriosis 2008
- Combination of estrogen and dioxin is involved in the pathogenesis of endometriosis by promoting chemokine secretion and invasion of endometrial stromal cells 2008
- Clinicopathological features and prognosis of Thai women with endometrioisis-associated ovarian carcinoma. 2007
- Ablation of Leptin Signaling Disrupts the Establishment, Development, and Maintenance of Endometriosis-Like Lesions in a Murine Model 2007
- Endometriosis, recurrent miscarriage and implantation failure: is there an immunological link? 2006
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- How Does Endometriosis Cause Infertility? 2003
- High Frequency of Endometrial Polyps in Endometriosis 2003
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