Endometriosis: associations with menorrhagia, infertility and oral contraceptives
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⤵ 70 in-corpus citations
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This retrospective study of 163 women found that 76% had menorrhagia, 10% complained of infertility, and 13% had used oral contraceptives, suggesting a possible role for estrogen sensitivity in endometriosis pathogenesis.
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Abstract
In a retrospective study of 163 women with endometriosis, 76% had a history of menorrhagia, a larger percentage than that which might be normally expected. Only 10% of the women complained of infertility, while 13% had used oral contraceptives regularly, a much smaller proportion than expected. These findings are discussed in terms of the pathogenesis of endometriosis and the possible prophylactic role of oral contraceptives. The authors suggest the possibility that increased sensitivity to estrogens may lead to the development of endometriosis in some women.
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References (11)
- A study of plasma progesterone, oestradiol-17beta, prolactin and LH levels, and of the luteal phase appearance of the ovaries in patients with endometriosis and infertility via openalex
- Conservative surgery for endometriosis in the infertile couple. via openalex
- Endometriosis. 3. Complete operations. Reasons, sequelae, treatment via openalex
- Endometriosis. I. Conservative operations via openalex
- ENDOMETRIOSIS: LONG-TERM OBSERVATION, WITH PARTICULAR REFERENCE TO INCIDENCE OF PREGNANCY via openalex
- Pelvic endometriosis: infertility and pelvic pain via openalex
- Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity via openalex
- The prevention, inhibition, palliation, and treatment of endometriosis via openalex
- W2794465143 via openalex
- W3143221338 via openalex
- W4299800166 via openalex
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- Regulated Expression of Interleukin-17 System at the Endometrial-Myometrial Interface: Implications for Adenomyosis 2024
- The Role of Peritoneal Immunity in Peritoneal Endometriosis and Related Infertility 2023
- Autoimmunity and infertility 2022
- Plasma and Peritoneal Poly (ADP-Ribose) Polymerase Levels in Patients with Endometriosis 2022
- Metformin Alleviates Endometriosis and Potentiates Endometrial Receptivity via Decreasing VEGF and MMP9 and Increasing Leukemia Inhibitor Factor and HOXA10 2022
- Auto-immunity and endometriosis 2021
- Endometriosis: A Retrospective Analysis on Diagnostic Data in a Cohort of 4,401 Patients 2021
- Age at Menarche, Duration of Monthly Flow and Cycle Length as Risk Factors for Endometriosis in Sub-Sahara Black African Women 2021
- The role of robotic surgery for endometriosis 2020
- Single-cell RNA sequencing of oocytes from ovarian endometriosis patients reveals a differential transcriptomic profile associated with lower quality 2019
- Infertility Associated to Endometriosis: Clarifying Some Important Controversies 2019
- Evaluation of miR-135a/b expression in endometriosis lesions 2019
- Ovarian Endometrioid and Clear-Cell Tumors 2019
- [Effect of GnRHa therapy following conservative laparoscopic surgery for endometriosis on clinical pregnant rate in patients with endometriosis-associated infertility] 2018
- Evaluation of PAI-1 in endometriosis using a homologous immunocompetent mouse model 2018
- The link between immunity, autoimmunity and endometriosis: a literature update 2018
- Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a multicenter, randomized, controlled trial 2017
- Biomarkers for Endometriosis in Saliva, Urine, and Peritoneal Fluid 2017
- Identifying biomarkers for non-invasive diagnosis of endometriosis 2016
- Implications of immune dysfunction on endometriosis associated infertility 2016
- Preoperative assessment and diagnosis of endometriosis: are we any closer? 2015
- Diminuição da expressão do miRNA 135 na fase secretora do ciclo menstrual em pacientes com endometriose 2014
- Associations between Estrogen Receptor Gene Polymorphisms and Endometriosis 2013
- Pelvic and Extragenital Endometriosis: A Review of the Surgical Management of Deeply Infiltrating Lesions 2013
- Evaluation of a panel of 28 biomarkers for the non-invasive diagnosis of endometriosis 2012
- Combined mRNA microarray and proteomic analysis of eutopic endometrium of women with and without endometriosis 2012
- Endometriosis and Oxidative Stress 2012
- Innovations in conservative endometriosis treatment: an updated review 2011
- Interleukin-1β induces cyclooxygenase-2 expression and promotes the invasive ability of human mesenchymal stem cells derived from ovarian endometrioma 2011
- Acquired haemophilia in severe pelvic endometriosis: a new association? 2011
- Abnormal regulation of chemokine TECK and its receptor CCR9 in the endometriotic milieu is involved in pathogenesis of endometriosis by way of enhancing invasiveness of endometrial stromal cells 2010
- Effects of simvastatin on the proliferation and apoptosis of human endometrial stromal cells from women with endometriosis 2010
- Oral contraceptives and risk of endometriosis: a systematic review and meta-analysis 2010
- Comparative study of human eutopic and ectopic endometrial mesenchymal stem cells and the development of an in vivo endometriotic invasion model 2010
- Medical treatment of endometriosis 2009
- Role of TGF-betas in normal human endometrium and endometriosis 2009
- The role of the oxidative-stress in the endometriosis-related infertility 2009
- Impact of endometriosis on quality of life: a pilot study 2009
- Eutopic endometrial interleukin-18 system mRNA and protein expression at the level of endometrial-myometrial interface in adenomyosis patients 2009
- Endometriosis 2008
- Combination of estrogen and dioxin is involved in the pathogenesis of endometriosis by promoting chemokine secretion and invasion of endometrial stromal cells 2008
- Clinicopathological features and prognosis of Thai women with endometrioisis-associated ovarian carcinoma 2007
- Ablation of leptin signaling disrupts the establishment, development, and maintenance of endometriosis-like lesions in a murine model 2007
- Endometriosis, recurrent miscarriage and implantation failure: is there an immunological link? 2006
- Aromatase inhibitors: the next generation of therapeutics for endometriosis? 2006
- [Endometriosis. Is it a problem of the immunological signs?] 2005
- High frequency of endometrial polyps in endometriosis 2003
- How Does Endometriosis Cause Infertility? 2003
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- pubmed
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